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Q 开关 Nd:YAG 治疗太田痣的长期随访:真的需要多次治疗吗?一例报告。

Long-Term Follow-Up for Q-Switched Nd:YAG Treatment of Nevus of Ota: Are High Number of Treatments Really Required? A Case Report.

机构信息

Laser Unit, Department of Dermatology, University of Rome Tor Vergata, Rome, Italy.

Department of Dermatology, University Magna Graecia of Catanzaro, Catanzaro, Italy.

出版信息

Photobiomodul Photomed Laser Surg. 2021 Feb;39(2):137-140. doi: 10.1089/photob.2020.4812. Epub 2020 Aug 5.

Abstract

Q-switched laser is considered a gold standard treatment for Nevus of Ota (NO). We report how few laser sessions in long intervals of time may achieve satisfying outcomes reducing the rate of possible procedure-linked side effects such as burning, cornea injuries, or hyperpigmentation. NO represents a congenital dermal melanocytosis in the trigeminal distribution majorly occurring in Asian individuals. Multiple reports have shown efficacy and safety of Q-switched laser for the treatment of this condition, but they were based on an empiric regimen, often leading to unnecessary overtreatments. At the best of our knowledge, no long-term follow-up observations of single laser sessions have been conducted to assess the proper intervals and number of treatments. A 36-year-old Asian woman, Fitzpatrick skin type IV with clinical diagnosis of NO, was treated with 1064 nm 6 ns Q-switched laser one session per year for a total of two sessions. Clinical result was valued by two physicians independently using standardized and polarized light. No use of general anesthesia or sedation was needed in our experience. Corneal shields have been used. After only two sessions of the Q-switched laser performed 1 year apart, the result was excellent with a 95% of clinical response. No side effect was observed. In our experience, Q-switched Nd:YAG laser is an effective treatment for NO with no necessity of high number of treatments. A larger population is needed to confirm this preliminary result.

摘要

调 Q 激光被认为是太田痣(NO)的金标准治疗方法。我们报告了在长时间间隔内进行多少次激光治疗可能会达到令人满意的效果,同时降低了可能与治疗相关的副作用(如灼伤、角膜损伤或色素沉着过度)的发生率。NO 是一种位于三叉神经分布区的先天性真皮黑色素细胞增多症,主要发生在亚洲人群中。多项报告表明 Q-开关激光治疗该疾病的疗效和安全性,但这些报告都是基于经验性的治疗方案,往往导致不必要的过度治疗。据我们所知,目前尚无关于单次激光治疗的长期随访观察来评估适当的治疗间隔和次数。

一位 36 岁的亚洲女性,Fitzpatrick 皮肤类型为 IV,临床诊断为太田痣,每年接受一次 1064nm6ns 调 Q 激光治疗,共进行了两次治疗。两名医生使用标准化和偏振光独立评估临床结果。根据我们的经验,不需要全身麻醉或镇静。使用了角膜保护罩。

在两次激光治疗时隔一年后,结果非常出色,临床反应率达到了 95%。未观察到任何副作用。

根据我们的经验,调 Q 钕:钇铝石榴石激光是治疗太田痣的有效方法,不需要进行多次治疗。需要更大的人群来证实这一初步结果。

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