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新冠病毒Delta变异株B.1.617.2的分析

Analysis of the Delta Variant B.1.617.2 COVID-19.

作者信息

Shiehzadegan Shayan, Alaghemand Nazanin, Fox Michael, Venketaraman Vishwanath

机构信息

Department of Basic Medical Sciences, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E 2nd St, Pomona, CA 91766, USA.

Department of Biology, University of California Irvine, Irvine, CA 92697, USA.

出版信息

Clin Pract. 2021 Oct 21;11(4):778-784. doi: 10.3390/clinpract11040093.

Abstract

With the delta variant of COVID-19, known as B.1.617.2, quickly ramping up infections around the world, we need to understand what makes this variant more contagious. One study has reported that the delta variant is 60% more transmissible than the alpha variant. As of August 2021, the delta variant has quickly become the dominant strain. Despite countries like the US, where most of the population is vaccinated, COVID-19 has made a resurgence in infections. Collectively, as a country, we ask: is it more deadly? What makes it more "contagious" or "transmissible"? This review article delves into the information we already know about the delta variant and how it compares with the other SARS-CoV-2 variants. The current vaccine companies like AstraZeneca, Pfizer/BioNTech, and Moderna have reported that their vaccines can provide protection against this variant but with a slightly reduced efficacy. In this article, we do a comprehensive review and summary of the delta B.1.617.2 variant and what makes it more contagious.

摘要

随着被称为B.1.617.2的新冠病毒德尔塔变种在全球迅速增加感染病例,我们需要了解是什么使得这个变种更具传染性。一项研究报告称,德尔塔变种的传播能力比阿尔法变种高60%。截至2021年8月,德尔塔变种已迅速成为主要毒株。尽管在美国等国家,大多数人口已接种疫苗,但新冠病毒感染病例仍再度出现。作为一个国家,我们共同问道:它更致命吗?是什么使其更“具传染性”或“可传播”?这篇综述文章深入探讨了我们已经了解到的关于德尔塔变种的信息,以及它与其他新冠病毒变种的比较情况。目前的疫苗公司,如阿斯利康、辉瑞/生物科技公司和莫德纳公司报告称,他们的疫苗可以提供针对这个变种的保护,但效力略有降低。在本文中,我们对B.1.617.2德尔塔变种以及使其更具传染性的因素进行了全面综述和总结。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/8544471/991a9f5d9e5b/clinpract-11-00093-g001.jpg

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