Brew B J
Aust N Z J Med. 1986 Oct;16(5):676-8. doi: 10.1111/j.1445-5994.1986.tb00011.x.
Records of the emergency medical admissions to a large teaching hospital over a one year period were examined for evidence of Wernicke's encephalopathy or Korsakoff's syndrome. It was found that only 0.4% of the population studied had the classical triad of Wernicke's encephalopathy, namely confusion, ophthalmoplegia, and ataxia. If two of these three criteria are allowed in the absence of other causes then 2.2% of the population had this limited Wernicke's encephalopathy or Korsakoff's syndrome. It is concluded that the diagnosis of Wernicke's encephalopathy should not rely on the presence of all three criteria; any two of the three in the absence of other causes will suffice for the diagnosis.
对一家大型教学医院一年期间的急诊入院记录进行了检查，以寻找韦尼克脑病或科萨科夫综合征的证据。结果发现，在所研究的人群中，只有0.4%的人具有韦尼克脑病的典型三联征，即意识模糊、眼肌麻痹和共济失调。如果在没有其他病因的情况下允许采用这三项标准中的两项，那么2.2%的人群患有这种局限性韦尼克脑病或科萨科夫综合征。结论是，韦尼克脑病的诊断不应依赖于所有三项标准的存在；在没有其他病因的情况下，三项标准中的任何两项就足以做出诊断。
