Bond N W, Homewood J
School of Behavioural Sciences, Macquarie University, NSW, Australia.
Neurotoxicol Teratol. 1991 Jul-Aug;13(4):353-5. doi: 10.1016/0892-0362(91)90083-9.
The conventional wisdom suggests that Korsakoff's psychosis, an amnesic disorder associated with prolonged alcohol consumption, is the chronic outcome of a thiamin deficiency first exhibited as Wernicke's encephalopathy. The present paper describes the debate in Australia over whether flour and alcoholic beverages should be fortified with thiamin, in an attempt to prevent Wernicke's encephalopathy and thus Korsakoff's psychosis. We conclude that the scientific evidence linking Wernicke's encephalopathy and Korsakoff's psychosis is tenuous. Certainly, it is not sufficient to support what would amount to mass medication.
传统观点认为，科萨科夫精神病是一种与长期饮酒相关的失忆症，是硫胺素缺乏的慢性后果，最初表现为韦尼克脑病。本文描述了澳大利亚关于面粉和酒精饮料是否应添加硫胺素以预防韦尼克脑病进而预防科萨科夫精神病的争论。我们得出结论，将韦尼克脑病和科萨科夫精神病联系起来的科学证据并不确凿。当然，这不足以支持相当于大规模用药的做法。
