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童年期受欺负在养育质量、应激性生活事件与成年期抑郁之间的关联中起中介作用。

Victimization in Childhood Mediates the Association Between Parenting Quality, Stressful Life Events, and Depression in Adulthood.

作者信息

Ishii Yoshitaka, Masuya Jiro, Morishita Chihiro, Higashiyama Motoki, Inoue Takeshi, Ichiki Masahiko

机构信息

Department of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.

Fuji Psychosomatic Rehabilitation Institute Hospital, Fujinomiya, Shizuoka, 418-0035, Japan.

出版信息

Neuropsychiatr Dis Treat. 2021 Oct 19;17:3171-3182. doi: 10.2147/NDT.S323592. eCollection 2021.

Abstract

BACKGROUND

Various stressors during childhood and adulthood, such as experiencing poor parenting, abuse, and harassment, have long-lasting effects on depression. The long-term effects of childhood stressors, such as childhood abuse and inappropriate parenting experiences, on adult depression are mediated by personality traits. In the present study, we hypothesized that parental bonding in childhood influences adulthood depression, and that this association is mediated by childhood victimization experiences and negative life event evaluations in adulthood. To test this hypothesis, multiple regression analysis and structural equation modeling were performed.

METHODS

A questionnaire survey, including Patient Health Questionnaire-9, victimization scale in childhood, Parental Bonding Instrument (PBI), and Life Experiences Survey was administered to 449 general adult volunteers (age: 41.1 ± 11.7 years; 196 men and 253 women). Multiple variables were analyzed by multiple regression analysis and structural equation modeling.

RESULTS

Multiple regression analysis demonstrated that victimization experiences in childhood affect adulthood depression independently of several other factors. Structural equation modeling showed that the "parental care" subscale of the PBI decreased adulthood depression directly, as well as indirectly through its effects on victimization experiences in childhood and negative life events. On the other hand, the "parental overprotection" subscale of the PBI increased adulthood depression directly, as well as indirectly through its effects on the experience of victimization in childhood and negative life events.

CONCLUSION

The present study indicates that the experience of victimization in childhood is a risk factor of adulthood depression. Furthermore, we found that parenting quality experienced in childhood influences adulthood depression, and that these effects are mediated by the experiences of victimization in childhood and negative life events in adulthood.

摘要

背景

童年和成年期的各种压力源,如经历不良养育、虐待和骚扰,会对抑郁症产生长期影响。童年压力源,如童年虐待和不适当的养育经历,对成年期抑郁症的长期影响是由人格特质介导的。在本研究中,我们假设童年时期的父母关系会影响成年期抑郁症,并且这种关联是由童年时期的受害经历和成年期负面生活事件评估介导的。为了验证这一假设,我们进行了多元回归分析和结构方程模型分析。

方法

对449名普通成年志愿者(年龄:41.1±11.7岁;男性196名,女性253名)进行问卷调查,包括患者健康问卷-9、童年受害量表、父母关系量表(PBI)和生活经历调查。通过多元回归分析和结构方程模型分析多个变量。

结果

多元回归分析表明,童年时期的受害经历独立于其他几个因素影响成年期抑郁症。结构方程模型显示,PBI的“父母关怀”子量表直接降低成年期抑郁症,同时也通过其对童年受害经历和负面生活事件的影响间接降低成年期抑郁症。另一方面,PBI的“父母过度保护”子量表直接增加成年期抑郁症,同时也通过其对童年受害经历和负面生活事件的影响间接增加成年期抑郁症。

结论

本研究表明,童年时期的受害经历是成年期抑郁症的一个风险因素。此外,我们发现童年时期的养育质量会影响成年期抑郁症,并且这些影响是由童年时期的受害经历和成年期负面生活事件介导 的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1438/8541763/4ce113d7f946/NDT-17-3171-g0001.jpg

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