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自动注射器 - 一种用于紧急情况和个人治疗的智能设备。

Autoinjector - A smart device for emergency cum personal therapy.

作者信息

Roy Anitha, Geetha Royapuram Veeraragavan, Magesh Anitha, Vijayaraghavan Rajagopalan, Ravichandran Veerasamy

机构信息

Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.

Department of Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.

出版信息

Saudi Pharm J. 2021 Oct;29(10):1205-1215. doi: 10.1016/j.jsps.2021.09.004. Epub 2021 Sep 20.

Abstract

Autoinjectors are self-injectable devices; they are important class of medical devices which can deliver drugs through subcutaneous or intramuscular route. They enclose prefilled syringes or cartridges which are driven by a spring system. The major benefits of this device are easy self-administration, improved patient compliance, reduced anxiety, and dosage accuracy. Immediate treatment during emergency conditions such as anaphylaxis, migraine, and status epilepticus or for chronic conditions like psoriasis, diabetes, multiple sclerosis, and rheumatoid arthritis, Reformulation of first-generation biologics, technical advancements, innovative designs, patient compliance, overwhelming interest for self-administration all these made entry of more and more autoinjectors into use. In this review, intensive efforts have been made for exploring the different types of currently available autoinjectors for the management of emergency and chronic diseases.

摘要

自动注射器是可自我注射的装置;它们是一类重要的医疗设备,能够通过皮下或肌肉注射途径给药。它们装有由弹簧系统驱动的预填充注射器或药筒。该装置的主要优点包括自我给药方便、患者依从性提高、焦虑减轻以及剂量准确。在诸如过敏反应、偏头痛和癫痫持续状态等紧急情况期间或针对牛皮癣、糖尿病、多发性硬化症和类风湿性关节炎等慢性疾病进行即时治疗、第一代生物制剂的重新配方、技术进步、创新设计、患者依从性、对自我给药的浓厚兴趣,所有这些因素使得越来越多的自动注射器投入使用。在本综述中,我们付出了巨大努力来探索目前可用于治疗紧急和慢性疾病的不同类型的自动注射器。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94f1/8523323/dce15e981c66/gr1.jpg

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