Cathedral Eye Clinic, 89-91 Academy Street, Belfast, BT1 2 LS, Northern Ireland, UK.
Department of Ophthalmology, Medical University of Innsbruck, Innsbruck, Austria.
Int Ophthalmol. 2022 Mar;42(3):1013-1020. doi: 10.1007/s10792-021-02086-4. Epub 2021 Oct 28.
It is well reported that dry eye symptoms can increase after many refractive surgery procedures. This study aims to provide a clinical understanding of the correlation of fluorescein tear film breakup time (FTBUT) with quality of vision (QoV) and dry eye symptoms following small incision lenticule extraction surgery (SMILE).
Patients electing to have SMILE surgery were subdivided into 2 groups: Group 1 included short preoperative FTBUTs of 3 to 6 seconds (s); Group 2 included long FTBUTs of ≥ 8 s. Uncorrected distance visual acuity, corrected distance visual acuity, manifest refraction, FTBUT, QoV and Ocular Surface Disease Index (OSDI) questionnaires were recorded 1 and 6 months postoperatively.
Thirty-nine subjects were included in each group. There was no significant difference in visual outcomes between the 2 groups at both the 1- and 6-month postoperative assessments. FTBUT remained significantly lower in group 1. Oxford staining was initially higher for group 1 at 1 month (P = 0.007), but there was no significant difference at 6 months (P = 0.180). There was no significant difference in QoV or OSDI scores between the 2 groups at both postoperative visits.
Low preoperative FTBUT (3-6 s) does not appear to negatively affect postoperative visual outcomes or results in a greater likelihood of dry eye symptoms and poor ocular surface compared to eyes with a longer preoperative FTBUT. These results suggest that a low preoperative FTBUT does not necessarily increase the likelihood of poor visual acuity, dry eyes symptoms, or poor ocular surface outcomes following SMILE surgery.
多项研究报道,许多屈光手术术后会出现干眼症状加重。本研究旨在了解飞秒激光小切口角膜基质透镜取出术(SMILE)后,泪膜破裂时间(FTBUT)与视觉质量(QoV)和干眼症状的相关性。
选择行 SMILE 手术的患者分为 2 组:术前 FTBUT 短(3-6 秒)的为组 1,术前 FTBUT 长(≥8 秒)的为组 2。记录患者术后 1 个月和 6 个月的未矫正远视力、矫正远视力、客观验光、FTBUT、QoV 和眼表疾病指数(OSDI)问卷。
每组 39 例。术后 1 个月和 6 个月,2 组的视力结果无显著差异。组 1 的 FTBUT 始终较低。术后 1 个月组 1 的 Oxford 染色评分较高(P = 0.007),但术后 6 个月无显著差异(P = 0.180)。术后 2 组 QoV 和 OSDI 评分均无显著差异。
术前 FTBUT 较低(3-6 秒)似乎不会对术后视力结果产生负面影响,与术前 FTBUT 较长的眼睛相比,也不会导致干眼症状和眼表不良的可能性增加。这些结果表明,SMILE 术后低术前 FTBUT 不一定会增加视力差、干眼症状或眼表不良结局的可能性。