Wong Christina S, Perry Kyler W, Rosenbaum Amy
College of Osteopathic Medicine, Touro University Nevada, Henderson, USA.
Obstetrics and Gynecology, Women's Health Associates of Southern Nevada, Las Vegas, USA.
Cureus. 2021 Sep 24;13(9):e18260. doi: 10.7759/cureus.18260. eCollection 2021 Sep.
Metoclopramide is a dopamine D2-receptor blocking agent commonly used to treat nausea, vomiting, and gastroparesis. Due to their mechanism of action, these drugs can lead to extrapyramidal side effects such as tardive dyskinesia. In this article, we report a case of a nulliparous gynecology patient who developed dyskinetic movements after intraoperative administration of metoclopramide. During further workup after stabilization, she was found to have several risk factors for tardive dyskinesia. As the occurrence of this phenomenon is somewhat rare, this case report aims to discuss the condition, associated risk factors, and differentiation from other diagnoses.
甲氧氯普胺是一种多巴胺D2受体阻断剂，常用于治疗恶心、呕吐和胃轻瘫。由于其作用机制，这些药物可导致锥体外系副作用，如迟发性运动障碍。在本文中，我们报告了一例未生育的妇科患者，在术中使用甲氧氯普胺后出现运动障碍。在病情稳定后的进一步检查中，发现她有几个迟发性运动障碍的危险因素。由于这种现象的发生较为罕见，本病例报告旨在讨论该病症、相关危险因素以及与其他诊断的鉴别。
