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免疫原性细胞死亡诱导剂增强癌症免疫治疗。

Immunogenic cell death inducers for enhanced cancer immunotherapy.

机构信息

College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China.

出版信息

Chem Commun (Camb). 2021 Nov 16;57(91):12087-12097. doi: 10.1039/d1cc04604g.

DOI:10.1039/d1cc04604g
PMID:34714302
Abstract

Inducing the immunogenic cell death (ICD) of cancer cells is an important method to improve the immunogenicity of tumor cells for enhanced cancer immunotherapy. Therefore, we discuss the ICD process and then highlight various ICD inducers and strategies for triggering the ICD of cancer cells. We hope that this Feature Article will inspire readers to develop more effective ICD inducers.

摘要

诱导癌细胞的免疫原性细胞死亡(ICD)是提高肿瘤细胞免疫原性以增强癌症免疫治疗的重要方法。因此,我们讨论了 ICD 过程,然后重点介绍了各种 ICD 诱导剂和策略,以触发癌细胞的 ICD。我们希望这篇专题文章能激发读者开发更有效的 ICD 诱导剂。

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