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EBT3 放射变色薄膜在腮腺癌放射治疗中的皮肤剂量测定

Skin Dosimetry with EBT3 Radiochromic Film in Radiotherapy of Parotid Cancer.

作者信息

Bahreyni Toossi Mohammad Taghi, Ghorbani Mahdi, Khorshidi Farideh, Mohammadi Mohammad, Mohamadian Nastaran, Akbari Fateme, Dayani Mahdie

机构信息

PhD, Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

PhD, Department of Biomedical Engineering and Medical Physics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Biomed Phys Eng. 2021 Oct 1;11(5):573-582. doi: 10.31661/jbpe.v0i0.1083. eCollection 2021 Oct.

Abstract

BACKGROUND

Skin is a sensitive organ and should be spared in radiotherapy and irradiation of skin in radiotherapy can cause to acute and late skin effects such as erythema, desquamation, epilation, color change, or even necrosis.

OBJECTIVE

The aim of the present study is to do skin dosimetry in radiotherapy of parotid cancer using Gafchromic EBT3 radiochromic film. EBT3 radiochromic films were calibrated in 0.2-5 Gy dose range.

MATERIAL AND METHODS

This is an experimental study in the field of radiotherapy physics. Treatment planning was performed on a RANDO phantom for treatment of parotid cancer by a clinical oncologist. Based on the treatment planning, the skin dose at various points in the overlapping region of right anterior-oblique and right posterior-oblique fields were measured using EBT3 radiochromic film.

RESULTS

The minimum and maximum skin doses in a fraction (with 2.0 Gy prescribed dose) were 0.50 Gy and 0.97 Gy, respectively. Based on these values, the total skin dose in 30 treatment fractions (for removed tumor) or in 35 treatment fractions (for unremoved tumor) was in the range of 15-33 Gy.

CONCLUSION

Based on the skin dosimetry results of parotid cancer radiotherapy using EBT3 films, it is predicted that there will occur mild skin reactions and these reactions can be neglected due to being mild.

摘要

背景

皮肤是一个敏感器官,在放射治疗中应避免照射,放射治疗中皮肤受照会导致急性和晚期皮肤反应,如红斑、脱屑、脱毛、颜色改变,甚至坏死。

目的

本研究旨在使用Gafchromic EBT3放射变色胶片对腮腺癌放射治疗进行皮肤剂量测定。EBT3放射变色胶片在0.2 - 5 Gy剂量范围内进行校准。

材料与方法

这是一项放射治疗物理领域的实验研究。由临床肿瘤学家在RANDO体模上进行腮腺癌治疗的治疗计划制定。根据治疗计划,使用EBT3放射变色胶片测量右前斜野和右后斜野重叠区域不同点的皮肤剂量。

结果

一次分割照射(处方剂量为2.0 Gy)中皮肤最小剂量和最大剂量分别为0.50 Gy和0.97 Gy。基于这些值,30次治疗分割(针对切除肿瘤)或35次治疗分割(针对未切除肿瘤)的总皮肤剂量在15 - 33 Gy范围内。

结论

基于使用EBT3胶片对腮腺癌放射治疗的皮肤剂量测定结果,预计会出现轻度皮肤反应,且由于反应轻微可忽略不计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e68e/8546163/f120b751f358/JBPE-11-573-g001.jpg

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