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在儿童腹泻治疗中添加蜂蜜与锌的效果。

The Effect of Adding Honey to Zinc in the Treatment of Diarrhea in Children.

作者信息

Mahyar Abolfazl, Ayazi Parviz, Shaftaroni Mohammad Reza, Oveisi Sonia, Dalirani Reza, Esmaeili Shiva

机构信息

Department of Pediatrics, Qazvin University of Medical Sciences, Qazvin, Iran.

Department of Pediatrics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Korean J Fam Med. 2022 May;43(3):188-192. doi: 10.4082/kjfm.21.0080. Epub 2021 Nov 2.

Abstract

BACKGROUND

Honey has been used in medicine since ancient times. Limited reports are available to indicate its antibacterial, antiviral, and antidiarrheal properties. This study aimed to determine the effect of honey on acute diarrhea in children.

METHODS

This randomized clinical trial included 80 children with acute diarrhea. Forty children received honey and zinc gluconate (trial group) and 40 received only zinc gluconate (control group). After treatment, vomiting/diarrhea duration, the recovery time, and the duration of hospitalization were compared between the groups.

RESULTS

Among the 40 children in the trial group, 19 were male and 21 were female. In the control group, 25 children were male and 15 female (P=0.26). After initiating treatment, the duration of diarrhea, recovery time, and the duration of hospitalization was significantly shorter in the trial group than in the control group (P<0.05).

CONCLUSION

This study showed that honey with zinc gluconate reduces the duration of diarrhea, accelerates the recovery time, and shortens the duration of hospitalization.

摘要

背景

蜂蜜自古以来就被用于医学。关于其抗菌、抗病毒和止泻特性的报道有限。本研究旨在确定蜂蜜对儿童急性腹泻的影响。

方法

这项随机临床试验纳入了80名急性腹泻儿童。40名儿童接受蜂蜜和葡萄糖酸锌(试验组),40名儿童仅接受葡萄糖酸锌(对照组)。治疗后,比较两组的呕吐/腹泻持续时间、恢复时间和住院时间。

结果

试验组的40名儿童中,19名男性,21名女性。对照组中,25名儿童为男性,15名女性(P=0.26)。开始治疗后,试验组的腹泻持续时间、恢复时间和住院时间明显短于对照组(P<0.05)。

结论

本研究表明,蜂蜜与葡萄糖酸锌一起可缩短腹泻持续时间,加快恢复时间,并缩短住院时间。

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Oral zinc for treating diarrhoea in children.口服锌治疗儿童腹泻
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Oral zinc for treating diarrhoea in children.口服锌治疗儿童腹泻
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本文引用的文献

1
Acute Diarrhea in Children.儿童急性腹泻
Srp Arh Celok Lek. 2015 Nov-Dec;143(11-12):755-62. doi: 10.2298/sarh1512755r.
3
Antimicrobial properties of honey.蜂蜜的抗菌特性。
Am J Ther. 2014 Jul-Aug;21(4):304-23. doi: 10.1097/MJT.0b013e318293b09b.
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Honey: its medicinal property and antibacterial activity.蜂蜜:其药用特性及抗菌活性。
Asian Pac J Trop Biomed. 2011 Apr;1(2):154-60. doi: 10.1016/S2221-1691(11)60016-6.
6
Acute diarrhea in adults and children: a global perspective.成人与儿童的急性腹泻:全球视角
J Clin Gastroenterol. 2013 Jan;47(1):12-20. doi: 10.1097/MCG.0b013e31826df662.
8
Honey and wound healing: an overview.蜂蜜与伤口愈合:概述。
Am J Clin Dermatol. 2011 Jun 1;12(3):181-90. doi: 10.2165/11538930-000000000-00000.

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