地氟沙星、依诺沙星和头孢哌酮治疗实验性产气肠杆菌心内膜炎的比较。
Comparison of difloxacin, enoxacin, and cefoperazone for treatment of experimental Enterobacter aerogenes endocarditis.
作者信息
Boscia J A, Kobasa W D, Kaye D
出版信息
Antimicrob Agents Chemother. 1987 Mar;31(3):458-60. doi: 10.1128/AAC.31.3.458.
Abstract
This study compared difloxacin administered orally, enoxacin administered orally, and cefoperazone administered intramuscularly for the treatment of experimental Enterobacter aerogenes endocarditis. Difloxacin significantly reduced bacterial counts of vegetations, as compared with enoxacin and cefoperazone. Enoxacin and cefoperazone did not differ significantly. This study demonstrated that difloxacin was significantly more effective than enoxacin and cefoperazone for the treatment of E. aerogenes endocarditis in rabbits.
摘要
本研究比较了口服双氟沙星、口服依诺沙星和肌肉注射头孢哌酮治疗实验性产气肠杆菌心内膜炎的效果。与依诺沙星和头孢哌酮相比，双氟沙星能显著降低赘生物的细菌数量。依诺沙星和头孢哌酮之间无显著差异。本研究表明，在治疗兔产气肠杆菌心内膜炎方面，双氟沙星比依诺沙星和头孢哌酮显著更有效。
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