Condé Kaba, Guelngar Carlos Othon, Mohamed Awada, Adjibaye Emmanuel, Cissé Fodé Abass
Department of Rheumatology, Ignace Deen National Hospital, University of Conakry, Conakry, GIN.
Department of Neurology, Ignace Deen National Hospital, University of Conakry, Conakry, GIN.
Cureus. 2021 Sep 27;13(9):e18332. doi: 10.7759/cureus.18332. eCollection 2021 Sep.
Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is a rare entity. It is frequently under-detected. We report the case of SAPHO syndrome in a 38-year-old woman, seen in consultation for pain and swelling of the anterior chest wall affecting the sternoclavicular and sternocostal joints predominantly on the right, and low back pain with an inflammatory appearance with peripheral damage, especially in the legs. We also found in our patient episodes of palmoplantar pustulosis. The diagnosis of SAPHO syndrome was retained in accordance with Kahn's diagnostic criteria, and the osteitis was confirmed by morphological examinations (CT scan, MRI, and bone scintigraphy). The patient was treated with non-steroidal anti-inflammatory drugs and methotrexate with good clinical improvement.
滑膜炎、痤疮、脓疱病、骨肥厚、骨炎（SAPHO）综合征是一种罕见病症。它常常未被充分检测出来。我们报告一例38岁女性的SAPHO综合征病例，该患者因前胸壁疼痛和肿胀前来会诊，主要累及右侧胸锁关节和胸肋关节，同时伴有炎性外观且外周有损伤的下背部疼痛，尤其是腿部。我们还在该患者身上发现了掌跖脓疱病发作。根据卡恩诊断标准确诊为SAPHO综合征，通过形态学检查（CT扫描、MRI和骨闪烁显像）证实存在骨炎。患者接受了非甾体抗炎药和甲氨蝶呤治疗，临床症状有明显改善。
