IEEE J Biomed Health Inform. 2022 May;26(5):2158-2168. doi: 10.1109/JBHI.2021.3124551. Epub 2022 May 5.
Accurate and continuous measurement of the human core body temperature by a wearable device is of great significance for human health care and disease monitoring. The current wearable thermometers ignore the physiological differences between individuals and the role of blood perfusion in thermoregulation, resulting in insufficient accuracy and limitations in terms of the measurement sites. This study proposed a novel personal model for measuring core body temperature by taking dynamic tissue blood perfusion and individual differences into consideration. The technique facilitates possible accurate core body temperature measurements from the skin surface of the wrist and forehead. First, the personal core body temperature model was established based on the thermal equilibrium between the human body and the measurement device, in which the tissue blood perfusion changes dynamically with tissue temperature. Then, the parameters of the personal model that imply individual physiological differences were obtained based on personal data collected daily. The results show that with the developed personal model, the accuracy of the measured body temperature from the wrist is close to that of the forehead model. The wrist model and the forehead model have a mean absolute error of 0.297 (SD = 0.078)°C and 0.224 (SD = 0.071)°C, respectively, which meets the accuracy and robustness requirements of practical applications. The personal models significantly improve the accuracy compared with that of the group model, especially for the wrist model.
通过可穿戴设备准确、连续地测量人体核心体温,对人体健康护理和疾病监测具有重要意义。目前的可穿戴温度计忽略了个体的生理差异和血液灌注在体温调节中的作用,导致测量精度不足,测量部位受限。本研究提出了一种新的个人模型,该模型考虑了动态组织血液灌注和个体差异,用于测量核心体温。该技术可从手腕和额头皮肤表面实现可能的准确核心体温测量。首先,基于人体与测量设备之间的热平衡,建立了个人核心体温模型,其中组织血液灌注随组织温度动态变化。然后,基于日常收集的个人数据,获得了个人模型中暗示个体生理差异的参数。结果表明,通过开发的个人模型,从手腕测量的体温精度接近额头模型。手腕模型和额头模型的平均绝对误差分别为 0.297°C(SD=0.078°C)和 0.224°C(SD=0.071°C),满足实际应用的精度和稳健性要求。与群体模型相比,个人模型显著提高了测量精度,尤其是手腕模型。