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海洋低聚多酚对患有肌肉减少症的老年人身体成分和身体能力的影响:一项初步研究。

Effects of marine oligomeric polyphenols on body composition and physical ability of elderly individuals with sarcopenia: a pilot study.

作者信息

Kwon Il-Su, Park Deuk-Su, Shin Hyeon-Cheol, Seok Myung-Gyu, Oh Jae-Keun

机构信息

Department of Health and Exercise Science, Korea National Sport University, Seoul, Republic of Korea.

Botamedi Inc., Seoul, Republic of Korea.

出版信息

Phys Act Nutr. 2021 Sep;25(3):1-7. doi: 10.20463/pan.2021.0014. Epub 2021 Sep 30.

Abstract

PURPOSE

We aimed to identify the effects of marine oligomeric polyphenol (MOP) intake in elderly individuals with sarcopenia.

METHODS

Older adults (aged 65 years or older) were recruited based on the diagnostic criterion for sarcopenia and were randomly assigned to the MOP intake group (n=10) or the placebo (PBO) intake group (n=10). To determine the effect of MOP intake received for four weeks, the pre- and post-intake body composition (weight, skeletal muscle mass, and bone density) and senior fitness tests were assessed.

RESULTS

Our results showed there were significant differences in the skeletal muscle mass (p=0.039), bone density (p=0.020), fat-free mass index (p=0.026), and 2.4 m up and go test (p=0.001) between pretest and post-test. There was a significant difference between the pre-test and post-test and an interaction effect for the one-leg stand test (p=0.010 and p=0.049, respectively). However, there were no significant differences in body fat percentage, calf circumference, grip strength, or the chair rise test.

CONCLUSION

Some variables exhibited significant differences in the pre- and post-assessments, and there was an interaction effect for the one-leg stand. However, this was insufficient to prove the effectiveness of MOP intake in improving sarcopenia. Therefore, additional studies are essential to examine the effects of MOP intake and exercise intervention on the body composition and fitness of patients over a longer period.

摘要

目的

我们旨在确定摄入海洋低聚多酚(MOP)对患有肌肉减少症的老年人的影响。

方法

根据肌肉减少症的诊断标准招募65岁及以上的老年人,并将其随机分为MOP摄入组(n = 10)或安慰剂(PBO)摄入组(n = 10)。为了确定四周MOP摄入的效果,评估了摄入前后的身体成分(体重、骨骼肌质量和骨密度)以及老年人健身测试。

结果

我们的结果显示,测试前和测试后在骨骼肌质量(p = 0.039)、骨密度(p = 0.020)、去脂体重指数(p = 0.026)和2.4米起立行走测试(p = 0.001)方面存在显著差异。单腿站立测试在测试前和测试后存在显著差异且有交互作用(分别为p = 0.010和p = 0.049)。然而,体脂百分比、小腿围度、握力或椅子起立测试没有显著差异。

结论

一些变量在前后评估中表现出显著差异,单腿站立存在交互作用。然而,这不足以证明摄入MOP对改善肌肉减少症的有效性。因此,有必要进行更多研究来检验长期摄入MOP和运动干预对患者身体成分和体能的影响。

相似文献

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How to Diagnose Sarcopenia in Korean Older Adults?如何诊断韩国老年人的肌肉减少症?
Ann Geriatr Med Res. 2018 Jun;22(2):73-79. doi: 10.4235/agmr.2018.22.2.73. Epub 2018 Jun 30.

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