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1型糖尿病患者胰腺的超声评估:一项病例对照研究。

Sonographic Evaluation of the Pancreas in Type 1 Diabetes Mellitus: A Case-control Study.

作者信息

Abdulrahman Safa, Ibrahim Ahmed Abdelrahim, Mohamed Mohamed Adam, Gameraddin Moawia, Alelyani Magbool

机构信息

Department of Diagnostic Radiology, Faculty of Radiological Sciences and Medical Imaging, Alzaiem Alazhari University, Khartoum, Sudan.

Department of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.

出版信息

J Med Ultrasound. 2021 Jan 30;29(3):167-170. doi: 10.4103/JMU.JMU_89_20. eCollection 2021 Jul-Sep.

DOI:10.4103/JMU.JMU_89_20
PMID:34729324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8515619/
Abstract

BACKGROUND

Pancreas is a vital insulin-producing gland, and it is subjected to various disorders which produce alteration in the morphology and function. Ultrasound (US) of the pancreas is sensitive for evaluating the gland and provides the accurate diagnosis of pancreatic diseases. The aim of this study is to determine whether there were alterations in pancreatic size and echogenicity in type 1 diabetes mellitus (DM).

METHODS

A total of 100 patients with Type-1 DM (insulin dependent) were examined using the ultrasonography. They were compared to 22 healthy controls. Measurements of the pancreas were performed on type 1 diabetic patients and controls.

RESULTS

Pancreatic diameters of the head, body, and tail of the pancreas were reduced in Type 1 DM versus controls (1.78 vs. 1.80 cm, 95% confidence interval [CI]: -0.147 -0.099, = 0.699 for the head of the pancreas; and 1.093 vs. 1.13 cm: 95% CI: -2.97-1.196, = 0.484 for the body of the pancreas; 1.12 vs. 1.46 cm, 95% CI: -0.491-0.194, < 0.001 for the tail of the pancreas). The echogenicity of the pancreas in patients with Type 1 DM increased significantly as the duration of the disease increased ( = 0.015).

CONCLUSION

Individuals with Type 1 DM have reduced pancreatic size in comparison with controls. Patients with Type 1 DM have increased echogenicity of the pancreas as the duration of the disease increased.

摘要

背景

胰腺是一个重要的产生胰岛素的腺体,它会受到各种疾病的影响,从而导致形态和功能的改变。胰腺超声(US)对评估该腺体很敏感,能准确诊断胰腺疾病。本研究的目的是确定1型糖尿病(DM)患者的胰腺大小和回声是否存在改变。

方法

共对100例1型糖尿病(胰岛素依赖型)患者进行了超声检查。将他们与22名健康对照者进行比较。对1型糖尿病患者和对照者的胰腺进行测量。

结果

与对照组相比,1型糖尿病患者胰腺头部、体部和尾部的直径减小(胰腺头部:1.78 vs. 1.80 cm,95%置信区间[CI]:-0.147 -0.099,P = 0.699;胰腺体部:1.093 vs. 1.13 cm,95% CI:-2.97 -1.196,P = 0.484;胰腺尾部:1.12 vs. 1.46 cm,95% CI:-0.491 -0.194,P < 0.001)。随着1型糖尿病患者病程的增加,胰腺的回声显著增强(P = 0.015)。

结论

与对照组相比,1型糖尿病患者的胰腺体积减小。随着病程的增加,1型糖尿病患者胰腺的回声增强。

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