Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University.
Department of Radiology, Kanazawa University Hospital.
Magn Reson Med Sci. 2023 Apr 1;22(2):253-262. doi: 10.2463/mrms.mp.2021-0087. Epub 2021 Nov 2.
This multi-scanner study aimed to investigate the validity of single breath-hold (BH) diffusion-weighted imaging (DWI) using simultaneous-multislice (SMS) echo-planar imaging in multiple abdominal organs to enable faster acquisition and reliable quantification of apparent diffusion coefficient (ADC).
SNR, geometric distortion (GD), and ADC in a phantom; the ADC in the liver, renal cortex, paraspinal muscle, spleen, and pancreas; and the signal intensity ratio of the portal vein-to-muscle (SIR) in healthy volunteers were compared between BH- and respiratory-triggered (RT) DWI with b-values of 0 and 800 s/mm in two different MRI scanners.
The phantom study showed that the SNR of BH-DWI was significantly lower than that of the RT-DWI (P < 0.05 for both scanners), whereas the GD and ADC of BH-DWI did not differ significantly from those of the RT-DWI (P = 0.09-0.60). In the volunteer study, the scan times were 23 seconds for BH-DWI and 184±33 seconds for RT-DWI, respectively. The ADC of the liver in BH-DWI was significantly lower than that in RT-DWI (P < 0.05 for both scanners), whereas there were no significant differences in the ADCs of the renal cortex, paraspinal muscle, spleen, or pancreas between BH-DWI and RT-DWI (P = 0.07-0.86). The SIR in BH-DWI was significantly smaller than in RT-DWI (P < 0.05 for both scanners).
The proposed method enables the acquisition of abdominal diffusion-weighted images in a single BH.
本多扫描仪研究旨在探讨在多个腹部器官中使用同时多层（SMS）回波平面成像进行单次屏气（BH）扩散加权成像（DWI）的有效性，以实现更快的采集和可靠的表观扩散系数（ADC）定量。
在两个不同的 MRI 扫描仪中，比较了体模中的 SNR、几何失真（GD）和 ADC；肝脏、肾皮质、脊柱旁肌肉、脾脏和胰腺的 ADC；以及健康志愿者门静脉-肌肉（SIR）的信号强度比，在 BH 和呼吸触发（RT）DWI 中，b 值分别为 0 和 800 s/mm。
体模研究表明，BH-DWI 的 SNR 明显低于 RT-DWI（两个扫描仪均为 P < 0.05），而 BH-DWI 的 GD 和 ADC 与 RT-DWI 无明显差异（P = 0.09-0.60）。在志愿者研究中，BH-DWI 的扫描时间为 23 秒，RT-DWI 为 184±33 秒。BH-DWI 中肝脏的 ADC 明显低于 RT-DWI（两个扫描仪均为 P < 0.05），而肾皮质、脊柱旁肌肉、脾脏或胰腺的 ADC 在 BH-DWI 和 RT-DWI 之间无显著差异（P = 0.07-0.86）。BH-DWI 中的 SIR 明显小于 RT-DWI（两个扫描仪均为 P < 0.05）。
该方法可在单次屏气中获取腹部扩散加权图像。
