Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China.
Front Endocrinol (Lausanne). 2021 Oct 18;12:707584. doi: 10.3389/fendo.2021.707584. eCollection 2021.
The success rate of assisted reproduction techniques (ART) has long been less than satisfactory albeit the great progress made in recent years, demonstrating the need for alternative options in the ART cycles. Growing evidence correlates the effect of intrauterine platelet-rich plasma (PRP) infusion on the endometrium with reassuring reproductive results. Thus, in this review, we focus on the current clinical and mechanical evidence on PRP and its effect on endometrial receptivity, and assess the features, benefits and limitations of the current studies and potential risks of PRP in ART.
尽管近年来辅助生殖技术（ART）取得了重大进展，但成功率一直不尽如人意，这表明在 ART 周期中需要替代方案。越来越多的证据表明，宫腔内富含血小板血浆（PRP）输注对子宫内膜的作用与令人安心的生殖结果相关。因此，在本综述中，我们重点关注 PRP 的当前临床和机械证据及其对子宫内膜容受性的影响，并评估当前研究的特征、益处和局限性以及 PRP 在 ART 中的潜在风险。
