Li Wei, Zhu Yueling, Lou Jingan, Chen Jie, Xie Xiaojun, Mao Jianhua
Department of Clinical Laboratory, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, China.
Department of Traditional Chinese Medicine, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, China.
Transl Pediatr. 2021 Sep;10(9):2281-2286. doi: 10.21037/tp-21-150.
This study aims to investigate the impact of protective measures and isolation on intestinal infection in children before and after COVID-19 outbreak in Hangzhou, China.
Data on outpatient visits, intestinal infection visits, and tests of adenovirus or rotavirus from electronic healthcare records were extracted in Children's Hospital of Zhejiang University School of Medicine during the COVID-19 outbreak (January-December, 2020), and be compared with those in 2019 during the same period.
We found that pediatric outpatient visits, patients with intestinal infection and its proportion from January to December of 2020 were significantly less than that in the same period of 2019. Furthermore, the numbers of outpatient visits and patients with intestinal infection were the lowest in February and elevated slowly from March to December in 2020. We also found significantly decreased number of completed tests for intestinal viruses, positive cases of adenovirus and rotavirus, positive rate of rotavirus during January-December, 2020. The positive rates of adenovirus from March to September and December of 2020 were significantly lower than the levels of the same period in 2019. The positive rate of rotavirus and adenovirus in all age groups in 2020 is lower than the level of all age groups in 2019.
The outpatient visits and intestinal, rotavirus and adenovirus infections in children significantly decreased during COVID-19 outbreak. Adequate protective measures and isolation in children may help to prevent intestinal virus infections in children.
本研究旨在调查中国杭州新冠疫情前后，防护措施和隔离对儿童肠道感染的影响。
从浙江大学医学院附属儿童医院的电子医疗记录中提取新冠疫情期间（2020年1月至12月）的门诊就诊数据、肠道感染就诊数据以及腺病毒或轮状病毒检测数据，并与2019年同期数据进行比较。
我们发现，2020年1月至12月的儿科门诊就诊人次、肠道感染患者及其所占比例均显著低于2019年同期。此外，2020年2月门诊就诊人次和肠道感染患者数量最低，3月至12月缓慢上升。我们还发现，2020年1月至12月肠道病毒检测完成数量、腺病毒和轮状病毒阳性病例数、轮状病毒阳性率均显著下降。2020年3月至9月以及12月的腺病毒阳性率显著低于2019年同期水平。2020年各年龄组的轮状病毒和腺病毒阳性率均低于2019年各年龄组水平。
新冠疫情期间儿童门诊就诊人次以及肠道、轮状病毒和腺病毒感染显著减少。对儿童采取充分的防护措施和隔离可能有助于预防儿童肠道病毒感染。
