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原发性抗磷脂抗体综合征表现为急性心肌梗死。

Primary Antiphospholipid Antibody Syndrome Presenting as Acute Myocardial Infarction.

机构信息

Department of Cardiology, Meitra Hospital, Kozhikode, Kerala, 673005 India.

出版信息

J Invasive Cardiol. 2021 Nov;33(11):E918. doi: 10.25270/jic/21.00199.

DOI:10.25270/jic/21.00199
PMID:34735357
Abstract

A 46-year-old woman with no significant past history presented to the emergency department with history of sudden-onset central chest discomfort and diaphoresis. With a preliminary diagnosis of acute myocardial infarction, she was subjected to coronary angiography, which showed occlusion of the distal left anterior descending artery with otherwise normal epicardial coronary arteries. Aspiration was performed in the vessel and yielded pinkish friable tissue. The histopathological examination revealed fibrin-rich thrombus. The patient was treated with enoxaparin and switched to oral anticoagulation with warfarin. On follow-up, the nodular mass on the mitral valve reduced considerably in size and she was advised that life-long anticoagulation was necessary.

摘要

一位 46 岁的女性,既往无明显病史,因突发心前区中央不适和出汗就诊于急诊科。初步诊断为急性心肌梗死,行冠状动脉造影检查,显示左前降支远段闭塞,而心外膜冠状动脉正常。血管内抽吸后得到粉红色易碎组织。组织病理学检查显示富含纤维蛋白的血栓。给予依诺肝素治疗,并转为华法林口服抗凝治疗。随访时,二尖瓣上的结节状肿块明显缩小,建议她需要终身抗凝。

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