Lobban Dawn, Gardner Jason, Matheis Robert
Envision Pharma Group, Wilmslow, UK.
McCann Health Medical Communications, Macclesfield, UK.
Curr Med Res Opin. 2022 Feb;38(2):189-200. doi: 10.1080/03007995.2021.1997221. Epub 2021 Nov 4.
We aimed to gather multi-stakeholder insights on key issues relating to plain language summaries (PLS) of company-sponsored medical research to inform future industry recognized guidelines.
We identified diverse stakeholders based on expertise, familiarity with PLS, and geographical location. A Working Group ( = 11) with extensive expertise in PLS developed an initial list of 14 questions relating to PLS, which were shared with stakeholders. We used a modified Delphi approach to prioritize the 10 key questions that were then used to structure stakeholder discussions to collect evidence on the key challenges and opportunities to inform best practice for PLS.
Overall, 29 stakeholders took part in the study, representing different professional sectors and geographies. There was strong alignment among stakeholders on the priority questions for PLS, with high response rates for both surveys (69% and 90%). Moderated online sessions were attended by 27/29 stakeholders and opportunities to improve PLS uptake were highlighted: developing industry-wide PLS guidelines would help define and maintain quality, including having a clear directive for when publications should have a PLS; further advocacy is needed by target audiences to ensure PLS become an established part of company-sponsored research publications; a searchable repository could facilitate discoverability and broad dissemination of PLS to multiple target audiences.
Key issues identified by stakeholders provide broad insights into the real and perceived barriers relating to PLS uptake. Each emerging theme presents a possible action that could accelerate PLS uptake and facilitate sharing of new medical research with lay audiences.
我们旨在收集多方利益相关者对于公司资助的医学研究的简明语言摘要（PLS）相关关键问题的见解，以为未来行业认可的指南提供参考。
我们根据专业知识、对PLS的熟悉程度以及地理位置确定了不同的利益相关者。一个在PLS方面具有广泛专业知识的工作组（n = 11）制定了一份与PLS相关的14个问题的初始清单，并与利益相关者分享。我们采用了一种改良的德尔菲方法对10个关键问题进行优先级排序，然后用这些问题构建利益相关者讨论，以收集关于关键挑战和机遇的证据，为PLS的最佳实践提供参考。
总体而言，29名利益相关者参与了该研究，代表了不同的专业领域和地理位置。利益相关者在PLS的优先问题上高度一致，两项调查的回复率都很高（分别为69%和90%）。27/29名利益相关者参加了线上主持会议，并强调了提高PLS采用率的机遇：制定全行业的PLS指南将有助于定义和维持质量，包括明确规定出版物何时应附有PLS；目标受众需要进一步宣传，以确保PLS成为公司资助研究出版物的既定组成部分；一个可搜索的知识库可以促进PLS被多个目标受众发现和广泛传播。
利益相关者确定的关键问题为与PLS采用相关的实际和感知障碍提供了广泛的见解。每个新出现的主题都提出了一项可能的行动，该行动可以加速PLS的采用，并促进与普通受众分享新的医学研究成果。
