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L.:植物化学、药理学、毒理学及民族药用方面的进展。

L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses.

作者信息

Wang Si-Yu, Zhao Hui, Xu Hong-Tao, Han Xiao-Dong, Wu Yun-Shan, Xu Fang-Fang, Yang Xiao-Bo, Göransson Ulf, Liu Bo

机构信息

The Second Clinical Medical College, and Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, China.

Guangzhou Key Laboratory of Chirality Research on Active Components of Traditional Chinese Medicine, Guangzhou, China.

出版信息

Front Pharmacol. 2021 Oct 19;12:675350. doi: 10.3389/fphar.2021.675350. eCollection 2021.

Abstract

is an aromatic medicinal herb. It is locally to India and distributed in China, Myanmar, Indonesia, Malaysia, and Thailand. is a Traditional Chinese Herb Medicine (TCHM), which has been applied to treat cold, dry cough, toothaches, rheumatism, hypertension and so on. In addition, it has been used widely as spices since its highly aromas. The aim of this review is to compile and update the current progresses of ethnomedicinal uses, phytochemistry, pharmacology and toxicology of . All the data on were based on different classical literary works, multiple electronic databases including SciFinder, Web of Science, PubMed, etc. The results showed that ninety-seven compounds have been identified from rhizome of , including terpenoids, phenolics, cyclic dipeptides, flavonoids, diarylheptanoids, fatty acids and esters. Modern pharmacology studies revealed that extracts or secondary metabolites of the herb possessed anti-inflammatory, anti-oxidant, anti-tumorous, anti-bacterial, and anti-angiogenesis effects, which were closely related to its abundant ethnomedicinal uses. In conclusion, although previous research works have provided various information of , more in-depth studies are still necessary to systemically evaluate phytochemistry, pharmacological activities, toxicity and quality control of this herb.

摘要

是一种芳香药草。它原产于印度,分布在中国、缅甸、印度尼西亚、马来西亚和泰国。是一种传统中草药,已被用于治疗感冒、干咳、牙痛、风湿病、高血压等。此外,由于其香气浓郁,它还被广泛用作香料。本综述的目的是汇编和更新关于的民族药用、植物化学、药理学和毒理学的当前进展。所有关于的数据均基于不同的经典文献、多个电子数据库,包括SciFinder、Web of Science、PubMed等。结果表明,已从的根茎中鉴定出97种化合物,包括萜类、酚类、环二肽、黄酮类、二芳基庚烷类、脂肪酸和酯类。现代药理学研究表明,该草药的提取物或次生代谢产物具有抗炎、抗氧化、抗肿瘤、抗菌和抗血管生成作用,这与其丰富的民族药用用途密切相关。总之,尽管先前的研究工作提供了关于的各种信息,但仍需要更深入的研究来系统地评估该草药的植物化学、药理活性、毒性和质量控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d331/8560697/94655d3c7bc5/fphar-12-675350-g001.jpg

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