Long Xuan-Ning, Han Feng, Wei Lin, Meng Fan-Cheng, Qu Shen-Yue, Chen Min
College of Pharmaceutical Sciences, Southwest University Chongqing 400715, China.
Chongqing Institute of Medical Plant Cultivation Chongqing 408435, China.
Zhongguo Zhong Yao Za Zhi. 2021 Oct;46(19):5020-5026. doi: 10.19540/j.cnki.cjcmm.20210706.201.
The chemical constituents in the ethyl acetate extract of Corydalis tomentella was isolated and purified with normal and reversed phase silica gel column chromatography, Sephadex LH-20, MCI, and semi-preparative HPLC. The compound structures were identified based on spectroscopic experiments and reported papers. Finally, eighteen compounds(1-18) were obtained from C. tomentella, including 17 alkaloids and 1 terpenoid. Among them, compound 1(tomentellaine A) was a novel alkaloid. Compounds 2-5, 7-14, and 16-18 were isolated from this plant for the first time.
采用正相和反相硅胶柱色谱、葡聚糖凝胶LH - 20、MCI以及半制备高效液相色谱法对伏生紫堇乙酸乙酯提取物中的化学成分进行分离纯化。基于光谱实验和已发表文献鉴定化合物结构。最终，从伏生紫堇中获得了18个化合物（1 - 18），包括17个生物碱和1个萜类化合物。其中，化合物1（伏生紫堇碱A）是一种新型生物碱。化合物2 - 5、7 - 14以及16 - 18首次从该植物中分离得到。
