在从撒哈拉以南非洲返回巴西的旅行者中分离出的高风险大肠杆菌 ST167 携带的 IncX3 质粒上的 OXA-181 碳青霉烯酶。
OXA-181 carbapenemase carried on an IncX3 plasmid in high-risk Escherichia coli ST167 isolated from a traveler returning from Sub-Saharan Africa to Brazil.
机构信息
Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Departamento de Análises Clínicas, Faculdade de Farmácia, Universidade de São Paulo, Brazil.
出版信息
Diagn Microbiol Infect Dis. 2022 Jan;102(1):115570. doi: 10.1016/j.diagmicrobio.2021.115570. Epub 2021 Oct 8.
Abstract
This is the first detection and genomic analysis of an OXA-181-carbapenemase-producing E. coli in Brazil, from a traveler returning from Sub-Saharan Africa. The ST167 isolate carries bla inserted in an IncX3 plasmid. This report illustrates the potential role of travelers as silent vectors for dissemination of high-risk resistant clones.
摘要
这是巴西首例从撒哈拉以南非洲旅行返回的患者中检出的产 OXA-181 碳青霉烯酶的大肠埃希菌，且该菌为 ST167 型，其所携带的 bla 插入在 IncX3 型质粒上。本报告说明了旅行者作为传播高危耐药克隆的“沉默”载体的潜在作用。
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