1Department of Cardiology, Split University Hospital Centre, Split, Croatia; 2University of Split School of Medicine, Split, Croatia; 3Department of Ophthalmology, Split University Hospital Centre, Split, Croatia.
Acta Clin Croat. 2021 Jun;60(2):314-316. doi: 10.20471/acc.2021.60.02.20.
Numerous disorders of coagulation and fibrinolysis have been reported in patients with thyroid diseases, especially with hyperthyroidism. Most articles are focused on deep vein thrombosis risk, however, few of them describe association between hyperthyroidism and pulmonary embolism. We report a case of a 43-year-old woman with long-term uncontrolled hyperthyroidism complicated by venous thromboembolism. The potential mechanisms could be endothelial dysfunction, decreased fibrinolytic activity, and increased levels of coagulation factors. Thyroid evaluation should be recommended in patients with unprovoked venous thromboembolic events.
许多与甲状腺疾病相关的凝血和纤溶障碍已被报道,尤其是甲状腺功能亢进症。大多数文章都集中在深静脉血栓形成的风险上,但很少有文章描述甲状腺功能亢进症与肺栓塞之间的关系。我们报告了一例 43 岁女性,患有长期未控制的甲状腺功能亢进症,并发静脉血栓栓塞症。潜在的机制可能是内皮功能障碍、纤溶活性降低和凝血因子水平升高。对于无明显诱因的静脉血栓栓塞事件患者,应建议进行甲状腺功能评估。