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口腔和食管的药物性损伤:综述。

Lesions in the oral cavity and esophagus caused by prescribed drugs: A review.

机构信息

Faculty of Medicine, University of Nis, Serbia.

Clinic for Gastroenterology and Hepatology, University Clinical Center, Nis, Serbia.

出版信息

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022 Mar;166(1):21-27. doi: 10.5507/bp.2021.059. Epub 2021 Nov 5.

Abstract

Almost all drugs, including some plant-based compounds, can have adverse effects, about 10% of which are expressed at the level of the digestive tract and in some cases resemble gastrointestinal diseases. Most commonly manifest as difficult and/or painful swallowing, nausea, vomiting, diarrhea and constipation. In rare cases, lesions caused by medications may be complicated by bleeding, strictures and perforations and can manifest in all segments of the gastrointestinal tract (GIT). The diagnosis is made from a detailed medical history and clinical examination inter alia. and best confirmed by proximal or distal endoscopy.

摘要

几乎所有的药物,包括一些植物化合物,都可能有不良反应,其中约 10%在消化道水平表现出来,在某些情况下类似于胃肠道疾病。最常见的表现为吞咽困难和/或疼痛、恶心、呕吐、腹泻和便秘。在极少数情况下,药物引起的病变可能会并发出血、狭窄和穿孔,并可在胃肠道(GIT)的所有节段表现出来。诊断主要依据详细的病史和临床检查,最好通过近端或远端内窥镜检查来确认。

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