National University of Natural Medicine, Helfgott Research Institute, 2220 SW 1st Ave, Portland, OR, United States.
Canby Clinic, 452 NW 1st Ave, Canby, OR, United States.
Complement Ther Med. 2021 Dec;63:102788. doi: 10.1016/j.ctim.2021.102788. Epub 2021 Nov 6.
The coronavirus disease 2019 (COVID-19) pandemic has led to significant morbidity and mortality. Although COVID-19 vaccination is available, therapeutic options are still needed. The goal of the present manuscript is to report on a treatment strategy used in a naturopathic medical practice for mild and moderate COVID-19.
A retrospective chart review was conducted of 30 consecutive patients diagnosed with mild and moderate COVID-19 who were provided multi-nutrient, herbal, and probiotic treatment in a rural, out-patient, naturopathic primary care setting.
The primary outcome was treatment safety; secondary outcomes included changes in symptoms, progression to severe COVID-19, incidence of long COVID, and recovery time.
No side effects or adverse events were reported from treatment and all patients experienced resolution of symptoms presumed to be associated with COVID-19 infection. One patient who had been ill for 28 days prior to presentation was hospitalized. Five patients had an illness duration of more than one month. Time to treatment was correlated with duration of illness post-treatment (r = 0.63, p < 0.001) and more symptoms at presentation was correlated with a longer duration of illness (r = 0.52, p < 0.01).
In this retrospective chart review, a multi-nutrient, herbal, and probiotic therapeutic approach for mild and moderate COVID-19 appeared to be well-tolerated. Delay in seeking treatment after symptom onset, as well as more symptoms at presentation, were correlated with a longer duration of illness. This treatment strategy may have clinical benefit, warranting prospective clinical trials with confirmed COVID-19 cases.
2019 年冠状病毒病（COVID-19）大流行导致了大量的发病率和死亡率。尽管有 COVID-19 疫苗，但仍需要治疗方法。本手稿的目的是报告一种在自然疗法医疗实践中用于轻度和中度 COVID-19 的治疗策略。
对 30 例连续诊断为轻度和中度 COVID-19 的患者进行了回顾性图表审查，这些患者在农村门诊自然疗法初级保健环境中接受了多种营养素、草药和益生菌治疗。
主要结果是治疗安全性；次要结果包括症状变化、进展为严重 COVID-19、长 COVID 的发生率和恢复时间。
治疗无副作用或不良反应，所有患者均经历了与 COVID-19 感染相关的症状缓解。一名在就诊前已患病 28 天的患者住院。5 名患者的病程超过一个月。治疗时间与治疗后疾病持续时间呈正相关（r=0.63，p<0.001），就诊时症状越多与疾病持续时间越长呈正相关（r=0.52，p<0.01）。
在这项回顾性图表审查中，一种用于轻度和中度 COVID-19 的多种营养素、草药和益生菌治疗方法似乎耐受性良好。症状出现后寻求治疗的时间延迟以及就诊时的更多症状与疾病持续时间延长有关。这种治疗策略可能具有临床益处，值得对确诊的 COVID-19 病例进行前瞻性临床试验。
