Department of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman, 11622, Jordan.
Department of Internal Medicine, University of Arkansas for Medical Center, Little Rock, AR, 72205, USA.
BMC Pulm Med. 2021 Nov 8;21(1):356. doi: 10.1186/s12890-021-01736-8.
Identifying trends of hospital admissions for respiratory diseases is crucial for public health and research to guide future clinical improvements for better outcomes. This study aims to define the trends of respiratory disease-related hospital admissions (RRHA) in England and Wales between 1999 and 2019.
An ecological study was conducted using hospital admission data taken from the Hospital Episode Statistics database in England and the Patient Episode Database for Wales. Hospital admissions data for respiratory diseases were extracted for the period between April 1999 and March 2019. The trend in hospital admissions was assessed using a Poisson model.
Hospital admission rate increased by 104.7% [from 1535.05 (95% CI 1531.71-1538.38) in 1999 to 3142.83 (95% CI 3138.39-3147.26) in 2019 per 100,000 persons, trend test, p < 0.01]. The most common causes were influenza and pneumonia, chronic lower respiratory diseases, other acute lower respiratory infections, which accounted for 26.6%, 26.4%, and 14.9%, respectively. The age group 75 years and above accounted for 34.1% of the total number of hospital admissions. Males contributed to 50.5% of the total number of hospital admissions. Hospital admission rate in females increased by 119.8% [from 1442.18 (95% CI 1437.66-1446.70) in 1999 to 3169.38 (95% CI 3163.11-3175.64) in 2019 per 100,000 persons, trend test, p < 0.001]. Hospital admission rate increased by 92.9% in males [from 1633.25 (95% CI 1628.32-1638.17) in 1999 to 3149.78 (95% CI 3143.46-3156.09) in 2019 per 100,000 persons, trend test, p < 0.001].
During the study period, hospital admissions rate due to respiratory diseases increased sharply. The rates of hospital admissions were higher among males for the vast majority of respiratory diseases. Further observational studies are warranted to identify risk factors for these hospital admissions and to offer relevant interventions to mitigate the risk.
识别呼吸疾病住院趋势对于公共卫生和研究至关重要，可指导未来的临床改进，以实现更好的结果。本研究旨在定义 1999 年至 2019 年期间英格兰和威尔士与呼吸疾病相关的住院趋势（RRHA）。
使用来自英格兰医院入院统计数据库和威尔士患者入院数据库的入院数据进行生态学研究。提取了 1999 年 4 月至 2019 年 3 月期间的呼吸疾病住院数据。使用泊松模型评估住院趋势。
住院率增长了 104.7%[1999 年为 1535.05（95%置信区间 1531.71-1538.38）/100,000 人，2019 年为 3142.83（95%置信区间 3138.39-3147.26）/100,000 人，趋势检验，p<0.01]。最常见的病因是流感和肺炎、慢性下呼吸道疾病和其他急性下呼吸道感染，分别占 26.6%、26.4%和 14.9%。75 岁及以上年龄组占总住院人数的 34.1%。男性占总住院人数的 50.5%。女性的住院率增长了 119.8%[1999 年为 1442.18（95%置信区间 1437.66-1446.70）/100,000 人，2019 年为 3169.38（95%置信区间 3163.11-3175.64）/100,000 人，趋势检验，p<0.001]。男性的住院率增长了 92.9%[1999 年为 1633.25（95%置信区间 1628.32-1638.17）/100,000 人，2019 年为 3149.78（95%置信区间 3143.46-3156.09）/100,000 人，趋势检验，p<0.001]。
在研究期间，因呼吸疾病导致的住院率急剧上升。在大多数呼吸疾病中，男性的住院率更高。需要进一步的观察性研究来确定这些住院的风险因素，并提供相关干预措施来降低风险。
