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骨囊肿硬化治疗:单中心经验

Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience.

作者信息

Kumar Deepak, Kumar Sanjeev, Kumar Dharmendra, Patel Brij Mohan, Kumar Ashish, Kumar Santosh, Waliullah Shah

机构信息

Orthopedic Surgery, King Georges Medical University, Lucknow, IND.

Department of Orthopedics, Mahamaya Government Medical College, Ambedkar Nagar, IND.

出版信息

Cureus. 2021 Oct 4;13(10):e18469. doi: 10.7759/cureus.18469. eCollection 2021 Oct.

Abstract

Introduction Sclerotherapy offers an alternative to surgery to treat an aneurysmal bone cyst (ABC). The present study's main objective was to assess the radiological efficacy of sclerotherapy in the healing of the cyst cavity secondary to biopsy-proven ABC on X-rays and assess clinical efficacy on pain, recurrence, and complications. Materials and methods Between 2016 and 2018, 26 patients (12 females, 14 males) with biopsy-proven ABC treated by sclerotherapy were included. All patients received an injection of polidocanol 3% intralesional as standard treatment under fluoroscopic guidance. Ossification was assessed on plain X-ray, and the pain was evaluated on a visual analog scale (VAS). Results Ossification was complete in 24 (92.3%) patients and partial in two (7.7%) patients. Eighteen patients (70%) were pain-free at the end of three months. There was an improvement in the VAS score, and clinically, there was a significant reduction in pain and swelling. Two patients developed recurrence within two years of follow-up, treated successfully by the re-application of intralesional polidocanol 3% injection. Discussion Sclerotherapy provides an effective, minimally invasive treatment for ABC and is particularly useful for deep lesions, challenging access for surgery and potentially damaging vital structures. The use of percutaneous polidocanol 3% under fluoroscopic control seems to improve the risk/benefit ratio. Its clinical and radiological efficacy makes sclerotherapy an alternative treatment option in ABC.  Level of evidence IV, prospective study.

摘要

引言

硬化疗法为治疗骨动脉瘤样囊肿(ABC)提供了一种手术替代方案。本研究的主要目的是评估硬化疗法对经活检证实的ABC继发囊肿腔在X射线下愈合的放射学疗效,并评估其对疼痛、复发及并发症的临床疗效。

材料与方法

纳入2016年至2018年间26例经活检证实接受硬化疗法治疗的ABC患者(12例女性,14例男性)。所有患者在透视引导下接受病灶内注射3%聚多卡醇作为标准治疗。通过普通X线评估骨化情况,采用视觉模拟评分法(VAS)评估疼痛程度。

结果

24例(92.3%)患者骨化完全,2例(7.7%)患者部分骨化。18例(70%)患者在3个月末时无痛。VAS评分有所改善,临床上疼痛和肿胀明显减轻。2例患者在随访两年内复发,再次病灶内注射3%聚多卡醇成功治疗。

讨论

硬化疗法为ABC提供了一种有效、微创的治疗方法,尤其适用于深部病变,手术入路困难且可能损害重要结构的情况。在透视控制下使用经皮3%聚多卡醇似乎可改善风险/效益比。其临床和放射学疗效使硬化疗法成为ABC的一种替代治疗选择。证据级别IV,前瞻性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebd5/8564749/d082b0a8a162/cureus-0013-00000018469-i01.jpg

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