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一名中年女性的多发性毛母质瘤

Multiple Pilomatricoma in a Middle-Aged Woman.

作者信息

Muhammad Shoaib, Yousaf Amman, Atiq Aribah, Munir Ahmed, Alam Syed I

机构信息

Urology, Ghulab Devi Hospital, Al-Aleem Medical College, Lahore, PAK.

Internal Medicine, McLaren Hospital, Flint, USA.

出版信息

Cureus. 2021 Oct 4;13(10):e18475. doi: 10.7759/cureus.18475. eCollection 2021 Oct.

DOI:10.7759/cureus.18475
PMID:34754640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8565392/
Abstract

Pilomatricomas are rare skin tumors related to hair follicles. They typically present in children, and the most common locations are head and neck. Pilomatricomas are usually painless; however, they can cause cosmetic problems. Treatment is decided on an individual basis and involves local excision. However, caution should be taken if the lesion is malignant, as resection with safe margins (0.5-1.0 cm) is determinant of the overall outcome. Radiotherapy is indicated in cases of residual tumor tissue or recurrence. The role of chemotherapy in pilomatricomas is still undetermined. We report a 55-year-old female with multiple lumps on her shoulder and back. The sonographic features of these lesions were typically consistent with pilomatricomas. The patient decided to opt for excision due to cosmetic reasons and the histopathology features were suggestive of pilomatricoma.

摘要

毛发瘤是一种与毛囊相关的罕见皮肤肿瘤。它们通常出现在儿童身上,最常见的部位是头颈部。毛发瘤通常无痛;然而,它们可能会导致美容问题。治疗是根据个体情况决定的,包括局部切除。但是,如果病变是恶性的,则应谨慎处理,因为安全切缘(0.5 - 1.0厘米)切除是总体预后的决定性因素。残留肿瘤组织或复发的病例需要进行放射治疗。化疗在毛发瘤中的作用仍未确定。我们报告了一名55岁女性,其肩部和背部有多个肿块。这些病变的超声特征通常与毛发瘤一致。由于美容原因,患者决定选择切除,组织病理学特征提示为毛发瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ea0/8565392/30ff1cd7eb94/cureus-0013-00000018475-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ea0/8565392/bd38027d1101/cureus-0013-00000018475-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ea0/8565392/5f8a419b336e/cureus-0013-00000018475-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ea0/8565392/30ff1cd7eb94/cureus-0013-00000018475-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ea0/8565392/bd38027d1101/cureus-0013-00000018475-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ea0/8565392/5f8a419b336e/cureus-0013-00000018475-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ea0/8565392/30ff1cd7eb94/cureus-0013-00000018475-i03.jpg

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本文引用的文献

1
Pilomatricoma (calcifying epithelioma): MDCT and MR imaging findings in 31 patients with radiological-pathological correlation.毛母质瘤(钙化上皮瘤):31 例患者的 MDCT 和 MR 成像表现与放射病理学相关性研究。
Eur J Radiol. 2018 Sep;106:92-99. doi: 10.1016/j.ejrad.2018.07.020. Epub 2018 Jul 21.
2
Updated view on epidemiology and clinical aspects of pilomatricoma in adults.成人毛发基质瘤的流行病学和临床方面的最新观点。
Int J Dermatol. 2017 Oct;56(10):1032-1036. doi: 10.1111/ijd.13732.
3
Retrospective study of pilomatricoma: 261 tumors in 239 patients.
毛母质瘤的回顾性研究:239例患者中的261个肿瘤。
Actas Dermosifiliogr. 2014 Sep;105(7):699-705. doi: 10.1016/j.ad.2014.01.003. Epub 2014 May 13.
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Anetodermic pilomatricoma: report of three cases.皮肤萎缩性毛母质瘤:三例报告
Int J Dermatol. 2013 Jun;52(6):735-8. doi: 10.1111/j.1365-4632.2011.05285.x.
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Recurrent malignant pilomatrixoma invading the cranial cavity: Improved local control with adjuvant radiation.复发性恶性毛母质瘤侵犯颅腔:辅助放疗改善局部控制
J Med Imaging Radiat Oncol. 2009 Feb;53(1):139-41. doi: 10.1111/j.1754-9485.2009.02049.x.
6
Mutations in exon 3 of the CTNNB1 gene (beta-catenin gene) in cutaneous adnexal tumors.皮肤附属器肿瘤中CTNNB1基因(β-连环蛋白基因)外显子3的突变
Am J Dermatopathol. 2009 May;31(3):248-55. doi: 10.1097/DAD.0b013e318198922a.
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Anetodermic pilomatricoma.皮肤萎缩性毛母质瘤
J Cutan Pathol. 2009 Jan;36(1):67-70. doi: 10.1111/j.1600-0560.2008.01008.x. Epub 2008 Aug 18.
8
Pilomatrix carcinoma: a clinicopathologic study of six cases and review of the literature.毛母质癌:6例临床病理研究及文献复习
Am J Dermatopathol. 2001 Oct;23(5):394-401. doi: 10.1097/00000372-200110000-00002.
9
A large rapidly growing pilomatrixoma on a lower eyelid.下眼睑上一个迅速生长的大型毛母质瘤。
Br J Ophthalmol. 2000 Oct;84(10):1203-4. doi: 10.1136/bjo.84.10.1203a.
10
Pilomatricoma (Malherbe). A clinical and histopathologic survey of 78 cases.毛母质瘤(马尔赫贝瘤)。78例临床与组织病理学研究。
Int J Dermatol. 1988 Sep;27(7):477-80. doi: 10.1111/j.1365-4362.1988.tb00924.x.