Javaeed Arslaan, Qamar Shanza, Ali Sundus, Mustafa Mir Ahmad Talha, Nusrat Areeba, Ghauri Sanniya Khan
Pathology, Poonch Medical College, Rawalakot, PAK.
Pathology, Rawalpindi Medical University, Rawalpindi, PAK.
Cureus. 2021 Oct 4;13(10):e18486. doi: 10.7759/cureus.18486. eCollection 2021 Oct.
Certain contemporary histology stains and methods are not the same as those used in the past. This progression has delved into the requirement for more precise, less complex, and efficient staining procedures. The objective of this study is to assess historical and contemporary stains and procedures, as well as the challenges surrounding their improvement. Carmine, hematoxylin, silver nitrate, Giemsa, trichome stain, Gram stain, and mauveine were among the first histological stains discovered in nature. Aside from their utility in the study of tissues at the time, they also laid the groundwork for the development of commercial dyes that are still in use today. Hematoxylin and eosin, Ziehl-Nielsen (ZN) stain, periodic acid-Schiff stain, and Grocott-Gomori methenamine silver stain are some of the most recently developed histological stains. The future of histological stains and processes appears to be influenced by technological advancements and the demand for cost-effective diagnostic approaches in the healthcare system. Thus, currently used histological stains appear to be economical, quick, and reliable tools for interpreting, archiving, and delivering essential diagnoses that could not be achieved by any other means.
某些当代组织学染色方法与过去使用的方法不同。这种发展深入探讨了对更精确、更简单且高效的染色程序的需求。本研究的目的是评估历史和当代的染色方法及程序，以及围绕其改进的挑战。胭脂红、苏木精、硝酸银、吉姆萨、番红染色、革兰氏染色和苯胺紫是自然界中最早发现的一批组织学染色剂。除了在当时对组织研究的实用性外，它们还为如今仍在使用的商业染料的开发奠定了基础。苏木精和伊红染色、萋尼（ZN）染色、过碘酸-希夫染色和格罗科特-高莫里六胺银染色是一些最新开发的组织学染色方法。组织学染色和程序的未来似乎受到技术进步以及医疗系统中对经济高效诊断方法需求的影响。因此，当前使用的组织学染色剂似乎是用于解释、存档和提供通过其他任何手段都无法实现的基本诊断的经济、快速且可靠的工具。
