Oxford University Hospitals NHS Foundation Trust, Oxford NIHR Biomedical Research Centre, Oxford, UK.
MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine and National Institutes for Health Research Biomedical Research Centre, University of Oxford, Oxford, UK.
Cell Rep Med. 2021 Oct 19;2(10):100433. doi: 10.1016/j.xcrm.2021.100433.
Platelets are anucleate but contain a rich repertoire of mRNAs. In this issue of , Shen and colleagues present platelet transcriptomes from patients with myeloproliferative neoplasms to study disease mechanisms and generate a predictive algorithm for fibrotic progression.
血小板无核,但含有丰富的 mRNA 谱。在本期的 中,Shen 及其同事展示了来自骨髓增殖性肿瘤患者的血小板转录组,以研究疾病机制并生成纤维化进展的预测算法。