Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning, P.R. China.
Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, P.R. China.
Nat Prod Res. 2023 Apr;37(8):1271-1276. doi: 10.1080/14786419.2021.2001810. Epub 2021 Nov 10.
A new anthraquinone, asperquinone A (), and four known anthraquinone derivatives - were isolated from the mangrove endophytic fungus sp. 16-5C. These structures were elucidated by spectroscopic analysis and the absolute configuration of was unambiguously determined by ECD calculation. Compounds - showed no significant inhibitory effect against protein tyrosine phosphatase B (MptpB).
从红树林内生真菌 sp. 16-5C 中分离得到一个新的蒽醌类化合物asperquinone A ()和四个已知的蒽醌衍生物。这些结构通过光谱分析阐明，通过ECD 计算确定了的绝对构型。化合物 - 对 MptpB 蛋白酪氨酸磷酸酶 B 没有明显的抑制作用。
