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一名14岁儿童的局灶性结节性增生:病例报告

Focal nodular hyperplasia in a 14-year-old child: A case report.

作者信息

Vahedifard Farzan, Mortezazadeh Masoud, Mofidi Abbas, Kashani Mehdi, Sharifi Rayeni Alireza

机构信息

. Iran University of Medical Sciences, Tehran, Iran.

Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Caspian J Intern Med. 2021;12(Suppl 2):S460-S463. doi: 10.22088/cjim.12.0.460.

DOI:10.22088/cjim.12.0.460
PMID:34760105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8559645/
Abstract

BACKGROUND

Focal nodular hyperplasia (FNH) is a benign rare liver neoplasm in children and includes only 2% of all pediatric liver tumors. Here we reported the case of a 14-year-old girl with vague flank pain who was managed conservatively.

CASE PRESENTATION

Our case is a 14-year-old child (female), with a 5 cm diameter lesion in the right lobe of the liver in CT scan, and histologic findings compatible with FNH. A solid mass lobulated contour, intense enhancement with a hypodense central area, possibly indicative of central scar, was seen. Despite her mild flank pain we did not insist on surgical resection and managed her conservatively. Her pain resolved 2 weeks later and an imaging follow-up with ultrasound 6 months later showed no increase in size or numbers.

CONCLUSION

FNH is an uncommon mass lesion in children. Our patient had mild symptomatic severity, and several guidelines recommend surgical treatment in this condition, but our team performed conservative and medical treatment for her and got the desired result. Therefore, the combination of these factors raises the importance of introducing the case. According to FNH's nature, stability, complications, and evaluation of pain are essential to avoid unnecessary surgeries.

摘要

背景

局灶性结节性增生(FNH)是儿童罕见的良性肝脏肿瘤,仅占所有儿童肝脏肿瘤的2%。在此,我们报告了一例14岁出现模糊侧腹痛的女孩,其接受了保守治疗。

病例介绍

我们的病例是一名14岁儿童(女性),CT扫描显示肝脏右叶有一个直径5厘米的病变,组织学检查结果与FNH相符。可见一个边界呈分叶状的实性肿块,强化明显,中央区域呈低密度,可能提示中央瘢痕。尽管她有轻度侧腹痛,但我们并未坚持手术切除,而是对她进行了保守治疗。她的疼痛在2周后缓解,6个月后的超声影像学随访显示肿块大小和数量均未增加。

结论

FNH是儿童罕见的肿块性病变。我们的患者症状较轻,一些指南建议对此情况进行手术治疗,但我们团队对她进行了保守和药物治疗并取得了预期效果。因此,这些因素共同凸显了介绍该病例的重要性。根据FNH的性质,稳定性、并发症以及对疼痛的评估对于避免不必要的手术至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca51/8559645/2e7904ec1af1/cjim-12-460-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca51/8559645/b65e935cc312/cjim-12-460-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca51/8559645/2e7904ec1af1/cjim-12-460-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca51/8559645/b65e935cc312/cjim-12-460-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca51/8559645/2e7904ec1af1/cjim-12-460-g002.jpg

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