Ghandehari Melika, Sadri Donia, Farhadi Sareh
Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Int J Prev Med. 2021 Sep 29;12:125. doi: 10.4103/ijpvm.IJPVM_489_19. eCollection 2021.
One of the concerns of cell phone users is prolonged exposure to harmful and potentially carcinogenic waves. This study was aimed to investigate the correlation between amount of cell phone use and related factors with percentage of micronucleus containing cells.
This descriptive study was conducted on selected patients referring to Islamic Azad University Faculty of Dentistry using cell phones regarding related inclusion and exclusion criteria. Papanicolaou staining method was approached for mucosal smears of samples and frequency of micronucleus containing cells and also, frequency of micronucleus in each cell were recorded for each sample; then, correlation of these findings with amount of daily cell phone usage was statistically analyzed using the calculation of Pearson correlation coefficient and preparation of regression analysis (backward) with significant level of lower than 0.05.
Of 100 samples, the frequency of micronucleus containing cells was 2.94% ± 1.89% and the frequency of micronucleus in each cell was 1.02% ± 1.68%. The amount of cell phone usage was significantly correlated with the frequency of micronucleus containing cells (r = 0.70, = 0.0001) and also with the frequency of micronucleus in each cell (r = 0.57, = 0.0001). Also, age and sex were not significantly correlated with the frequency of micronucleus containing cells ( = 0.47 and 0.32) and also with the frequency of micronucleus in each cell, respectively ( = 0.16 and 0.27).
The present study showed that the increased amount of cell phone usage had a strong and significant correlation with the higher frequency of the micronucleus containing cells and the higher frequency of micronucleus in each cell in the buccal mucosa. Also, the related factors as age and sex were not significantly correlated with the frequency of micronucleus containing buccal mucosa cells.
手机用户的担忧之一是长期暴露于有害且可能致癌的电波中。本研究旨在调查手机使用量及相关因素与含微核细胞百分比之间的相关性。
本描述性研究针对符合相关纳入和排除标准、使用手机的选定患者，在伊斯兰阿扎德大学牙科学院进行。采用巴氏染色法对样本的黏膜涂片进行处理，记录每个样本中含微核细胞的频率以及每个细胞中微核的频率；然后，通过计算皮尔逊相关系数并进行显著性水平低于0.05的回归分析（向后法），对这些结果与每日手机使用量之间的相关性进行统计学分析。
在100个样本中，含微核细胞的频率为2.94%±1.89%，每个细胞中微核的频率为1.02%±1.68%。手机使用量与含微核细胞的频率显著相关（r = 0.70，P = 0.0001），也与每个细胞中微核的频率显著相关（r = 0.57，P = 0.0001）。此外，年龄和性别与含微核细胞的频率分别无显著相关性（P = 0.47和0.32），与每个细胞中微核的频率也分别无显著相关性（P = 0.16和0.27）。
本研究表明，手机使用量的增加与颊黏膜中含微核细胞的较高频率以及每个细胞中微核的较高频率密切相关且具有显著相关性。此外，年龄和性别等相关因素与颊黏膜含微核细胞的频率无显著相关性。
