Lam W K, Hawkins B R, Kung I T, So S Y
Br J Dis Chest. 1986 Oct;80(4):370-4. doi: 10.1016/0007-0971(86)90090-2.
A high incidence rate of lung cancer with preponderance of adenocarcinoma in non-smokers has been reported in women of southern Chinese ethnic origin. Thirty-three southern Chinese female patients with primary adenocarcinoma of the lung, all lifelong non-smokers, were typed for HLA-A and B antigens to study the possibility of genetically determined susceptibility factors. The antigen frequencies were compared with those of 110 healthy controls. No significant difference in antigen frequencies was found in the patients compared with controls. Studies on other possible factors determining susceptibility to lung cancer in Chinese women are necessary.
据报道，在中国南方汉族女性中，肺癌发病率较高，且腺癌占优势。对33名中国南方原发性肺腺癌女性患者（均为终身不吸烟者）进行了HLA - A和B抗原分型，以研究基因决定的易感性因素的可能性。将抗原频率与110名健康对照者的频率进行了比较。与对照组相比，患者的抗原频率没有显著差异。有必要对决定中国女性肺癌易感性的其他可能因素进行研究。
