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接种 mRNA-1273 新型冠状病毒疫苗后出现左侧贝尔麻痹:一例病例报告。

Left Bell's palsy following the first dose of mRNA-1273 SARS-CoV-2 vaccine: A case report.

机构信息

Department of Radiology, ASST Fatebenefratelli Sacco, Milano, Ospedale Fatebenefratelli, Piazza Principessa Clotilde 3, 20121 Milan, Italy.

Department of Neurology, ASST Fatebenefratelli Sacco, Milano, Ospedale Fatebenefratelli, Piazza Principessa Clotilde 3, 20121 Milan, Italy.

出版信息

Clin Imaging. 2022 Feb;82:1-4. doi: 10.1016/j.clinimag.2021.10.010. Epub 2021 Nov 4.

Abstract

Even though no definitive link has been established, Bell's palsy has been described as a potential side effect of SARS-CoV-2 mRNA vaccines in a few reports, and the US Food and Drug Administration has recommended strict surveillance of its occurrence in the vaccinated general population. We present the case of a previously healthy 35-year-old female patient who developed Bell's palsy 12 h after receiving the first dose of the mRNA-1273 vaccine. Her general practitioner performed the diagnosis, and corticosteroid treatment was initiated, with slow symptoms improvement. The neurologist's evaluation and a contrast-enhanced brain Magnetic Resonance Imaging revealed a subtle enhancement of the left facial nerve, confirming the diagnosis of Bell's palsy.

摘要

尽管尚未确定明确的关联,但有少数报道称贝尔麻痹是 SARS-CoV-2 mRNA 疫苗的潜在副作用之一,美国食品和药物管理局已建议在接种疫苗的普通人群中严格监测其发生情况。我们报告了一例先前健康的 35 岁女性患者,她在接种 mRNA-1273 疫苗第一剂后 12 小时出现贝尔麻痹。她的全科医生做出了诊断,并开始使用皮质类固醇治疗,症状缓慢改善。神经科医生的评估和对比增强脑磁共振成像显示左侧面神经轻度增强,确诊为贝尔麻痹。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5337/8566211/30b5967d068a/gr1_lrg.jpg

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