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一种使用局部二值模式、双树复数小波变换和卷积神经网络在胸部X光图像上检测新冠病毒的新型深度学习管道。

A new deep learning pipeline to detect Covid-19 on chest X-ray images using local binary pattern, dual tree complex wavelet transform and convolutional neural networks.

作者信息

Yasar Huseyin, Ceylan Murat

机构信息

Ministry of Health of Republic of Turkey, Ankara, Turkey.

Faculty of Engineering and Natural Sciences, Department of Electrical and Electronics Engineering, Konya Technical University, Konya, Turkey.

出版信息

Appl Intell (Dordr). 2021;51(5):2740-2763. doi: 10.1007/s10489-020-02019-1. Epub 2020 Nov 4.

Abstract

In this study, which aims at early diagnosis of Covid-19 disease using X-ray images, the deep-learning approach, a state-of-the-art artificial intelligence method, was used, and automatic classification of images was performed using convolutional neural networks (CNN). In the first training-test data set used in the study, there were 230 X-ray images, of which 150 were Covid-19 and 80 were non-Covid-19, while in the second training-test data set there were 476 X-ray images, of which 150 were Covid-19 and 326 were non-Covid-19. Thus, classification results have been provided for two data sets, containing predominantly Covid-19 images and predominantly non-Covid-19 images, respectively. In the study, a 23-layer CNN architecture and a 54-layer CNN architecture were developed. Within the scope of the study, the results were obtained using chest X-ray images directly in the training-test procedures and the sub-band images obtained by applying dual tree complex wavelet transform (DT-CWT) to the above-mentioned images. The same experiments were repeated using images obtained by applying local binary pattern (LBP) to the chest X-ray images. Within the scope of the study, four new result generation pipeline algorithms having been put forward additionally, it was ensured that the experimental results were combined and the success of the study was improved. In the experiments carried out in this study, the training sessions were carried out using the k-fold cross validation method. Here the k value was chosen as 23 for the first and second training-test data sets. Considering the average highest results of the experiments performed within the scope of the study, the values of sensitivity, specificity, accuracy, F-1 score, and area under the receiver operating characteristic curve (AUC) for the first training-test data set were 0,9947, 0,9800, 0,9843, 0,9881 and 0,9990 respectively; while for the second training-test data set, they were 0,9920, 0,9939, 0,9891, 0,9828 and 0,9991; respectively. Within the scope of the study, finally, all the images were combined and the training and testing processes were repeated for a total of 556 X-ray images comprising 150 Covid-19 images and 406 non-Covid-19 images, by applying 2-fold cross. In this context, the average highest values of sensitivity, specificity, accuracy, F-1 score, and AUC for this last training-test data set were found to be 0,9760, 1,0000, 0,9906, 0,9823 and 0,9997; respectively.

摘要

在这项旨在利用X射线图像对新冠肺炎疾病进行早期诊断的研究中,采用了深度学习方法,这是一种先进的人工智能方法,并使用卷积神经网络(CNN)对图像进行自动分类。在该研究中使用的第一个训练测试数据集中,有230张X射线图像,其中150张为新冠肺炎图像,80张为非新冠肺炎图像;而在第二个训练测试数据集中,有476张X射线图像,其中150张为新冠肺炎图像,326张为非新冠肺炎图像。因此,分别针对两个主要包含新冠肺炎图像和主要包含非新冠肺炎图像的数据集提供了分类结果。在该研究中,开发了一种23层的CNN架构和一种54层的CNN架构。在研究范围内,直接在训练测试过程中使用胸部X射线图像以及通过对上述图像应用双树复数小波变换(DT-CWT)获得的子带图像来获取结果。对胸部X射线图像应用局部二值模式(LBP)获得的图像也重复进行了相同的实验。在研究范围内,另外还提出了四种新的结果生成管道算法,确保将实验结果进行合并并提高了研究的成功率。在本研究中进行的实验中,训练环节采用k折交叉验证方法。此处,对于第一个和第二个训练测试数据集,k值均选择为23。考虑到在研究范围内进行的实验的平均最高结果,第一个训练测试数据集的灵敏度、特异性、准确率、F1分数以及受试者工作特征曲线下面积(AUC)的值分别为0.9947、0.9800、0.9843、0.9881和0.9990;而对于第二个训练测试数据集,它们分别为0.9920、0.9939、0.9891、0.9828和0.9991。在研究范围内,最后,将所有图像合并,并通过应用2折交叉对总共556张X射线图像(包括150张新冠肺炎图像和406张非新冠肺炎图像)重复进行训练和测试过程。在此背景下,发现最后这个训练测试数据集的灵敏度、特异性、准确率、F1分数以及AUC的平均最高值分别为0.9760、1.0000、0.9906、0.9823和0.9997。

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