Nguyen Chi Thanh, Han Jong-Man, Tran Van Huong, Jeong Hun, Kim Eun Sook
Department of Materials Technology, Faculty of Applied Sciences, Ho Chi Minh City University of Technology and Education, Ho Chi Minh City, 700000, Viet Nam.
Department of Physical Therapy, Daegu Health College, Daegu, 41453, Republic of Korea.
Clin Cosmet Investig Dermatol. 2021 Nov 2;14:1603-1612. doi: 10.2147/CCID.S336280. eCollection 2021.
In this study, a high-efficiency extract (SCE) produced by the fermentation of effective microorganisms (EM) was used as an antioxidant material in preparing cosmetic products.
We conducted the study by extracting via EM fermentation to increase the efficiency. Tyrosinase inhibitory factor analysis, pH, and thermal stability were measured to verify the properties of the prepared products.
The efficacy and whitening effects of the prepared substances were verified using tyrosinase inhibitory factor analysis. As a result, it was found that both the SCE and SCE fermentation (SCEF) exhibited high, naturally originating, antioxidation ability. In addition, the pH and thermal stability of the substances were evaluated to optimize the cosmetic fabrication conditions. In this context, as the concentration of the added extract increased, the pH value decreased. The evaluation of safety and stability indicated that the substances contained effective chemical components having antioxidant activity, suppressing skin aging, and whitening effects in a weak acid range consistent with a pH of 6.25-2.98. Furthermore, there were no safety problems with the use of the obtained products even after they had been stored for 60 days.
The SCE substance is demonstrated as a possible material for cosmetic application.
在本研究中，由有效微生物（EM）发酵产生的高效提取物（SCE）被用作制备化妆品的抗氧化材料。
我们通过EM发酵进行提取以提高效率来开展本研究。测量酪氨酸酶抑制因子分析、pH值和热稳定性以验证所制备产品的性质。
使用酪氨酸酶抑制因子分析验证了所制备物质的功效和美白效果。结果发现，SCE和SCE发酵物（SCEF）均表现出高的、天然来源的抗氧化能力。此外，对这些物质的pH值和热稳定性进行了评估以优化化妆品制造条件。在此情况下，随着添加提取物浓度的增加，pH值降低。安全性和稳定性评估表明，这些物质含有具有抗氧化活性、抑制皮肤衰老以及在pH值为6.25 - 2.98的弱酸范围内具有美白效果的有效化学成分。此外，所获得的产品即使储存60天后使用也不存在安全问题。
SCE物质被证明是一种可能用于化妆品应用的材料。
