Dawes C
J Dent Res. 1987 Feb;66 Spec No:648-53. doi: 10.1177/00220345870660S107.
This paper discusses methods for collection of both whole saliva and individual gland secretions, the normal ranges of salivary flow rate, the effects of physiological variables which influence flow rate, and the role of saliva in oral sugar clearance. The physiological basis for the sensation of dry mouth is discussed, and a new concept is advanced which states that the sensation of dry mouth will occur when the salivary flow rate is less than the sum of the rates of water absorption and evaporation from the mouth. In a study of the effects of anticholinergic agents on salivary flow, the subjects experienced the sensation of dry mouth when the normal flow rate of unstimulated saliva was reduced by from 40 to 50%.
本文讨论了收集全唾液和单个腺体分泌物的方法、唾液流速的正常范围、影响流速的生理变量的作用以及唾液在口腔糖分清除中的作用。讨论了口干感觉的生理基础，并提出了一个新的概念，即当唾液流速低于口腔水吸收和蒸发速率之和时，就会出现口干的感觉。在一项关于抗胆碱能药物对唾液分泌影响的研究中，当未刺激唾液的正常流速降低40%至50%时，受试者会感到口干。
