Wang Hui, Zhang Biao, Zhang Jianhong, He Xiangnan, Liu Fukang, Cui Jingjing, Lu Zhe, Hu Guang, Yang Jun, Zhou Zhe, Wang Runze, Hou Xingyu, Ma Luankexin, Ren Panyu, Ge Qi, Li Peng, Huang Wei
Frontiers Science Center for Flexible Electronics (FSCFE), Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering (IBME), Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China.
Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
ACS Appl Mater Interfaces. 2021 Nov 24;13(46):55507-55516. doi: 10.1021/acsami.1c15636. Epub 2021 Nov 12.
We report a facile but general method to prepare highly water-soluble and biocompatible photoinitiators for digital light processing (DLP)-based 3D printing of high-resolution hydrogel structures. Through a simple and straightforward one-pot procedure, we can synthesize a metal-phenyl(2,4,6-trimethylbenzoyl)phosphinates (M-TMPP)-based photoinitiator with excellent water solubility (up to ∼50 g/L), which is much higher than that of previously reported water-soluble photoinitiators. The M-TMPP aqueous solutions show excellent biocompatibility, which meets the prerequisite for biomedical applications. Moreover, we used M-TMPP to prepare visible light (405 nm)-curable hydrogel precursor solutions for 3D printing hydrogel structures with a high water content (80 wt %), high resolution (∼7 μm), high deformability (more than 80% compression), and complex geometry. The printed hydrogel structures demonstrate great potential in flexible electronic sensors due to the fast mechanical response and high stability under cyclic loadings.
我们报道了一种简便通用的方法，用于制备高水溶性且生物相容性良好的光引发剂，用于基于数字光处理（DLP）的高分辨率水凝胶结构3D打印。通过简单直接的一锅法程序，我们可以合成一种基于金属苯基（2,4,6-三甲基苯甲酰基）次膦酸盐（M-TMPP）的光引发剂，其具有出色的水溶性（高达约50 g/L），远高于先前报道的水溶性光引发剂。M-TMPP水溶液表现出优异的生物相容性，满足生物医学应用的前提条件。此外，我们使用M-TMPP制备了可见光（405 nm）可固化的水凝胶前体溶液，用于3D打印具有高含水量（80 wt%）、高分辨率（约7μm）、高可变形性（超过80%压缩率）和复杂几何形状的水凝胶结构。由于在循环载荷下具有快速的机械响应和高稳定性，打印出的水凝胶结构在柔性电子传感器中显示出巨大潜力。
