Zhang Biao, Li Shiya, Hingorani Hardik, Serjouei Ahmad, Larush Liraz, Pawar Amol A, Goh Wei Huang, Sakhaei Amir Hosein, Hashimoto Michinao, Kowsari Kavin, Magdassi Shlomo, Ge Qi
Digital Manufacturing and Design Centre, Singapore University of Technology and Design, 487372, Singapore.
J Mater Chem B. 2018 May 28;6(20):3246-3253. doi: 10.1039/c8tb00673c. Epub 2018 Apr 23.
We report a method to prepare highly stretchable and UV curable hydrogels for high resolution DLP based 3D printing. Hydrogel solutions were prepared by mixing self-developed high-efficiency water-soluble TPO nanoparticles as the photoinitiator with an acrylamide-PEGDA (AP) based hydrogel precursor. The TPO nanoparticles make AP hydrogels UV curable, and thus compatible with the DLP based 3D printing technology for the fabrication of complex hydrogel 3D structures with high-resolution and high-fidelity (up to 7 μm). The AP hydrogel system ensures high stretchability, and the printed hydrogel sample can be stretched by more than 1300%, which is the most stretchable 3D printed hydrogel. The printed stretchable hydrogels show an excellent biocompatibility, which allows us to directly 3D print biostructures and tissues. The great optical clarity of the AP hydrogels offers the possibility of 3D printing contact lenses. More importantly, the AP hydrogels are capable of forming strong interfacial bonding with commercial 3D printing elastomers, which allows us to directly 3D print hydrogel-elastomer hybrid structures such as a flexible electronic board with a conductive hydrogel circuit printed on an elastomer matrix.
我们报道了一种制备用于基于高分辨率数字光处理（DLP）的3D打印的高拉伸性且可紫外光固化水凝胶的方法。水凝胶溶液是通过将自行研发的作为光引发剂的高效水溶性TPO纳米颗粒与基于丙烯酰胺-聚乙二醇二丙烯酸酯（AP）的水凝胶前体混合制备而成。TPO纳米颗粒使AP水凝胶可紫外光固化，从而与基于DLP的3D打印技术兼容，用于制造具有高分辨率和高保真度（高达7μm）的复杂水凝胶3D结构。AP水凝胶体系确保了高拉伸性，打印出的水凝胶样品可拉伸超过1300%，这是最具拉伸性的3D打印水凝胶。打印出的可拉伸水凝胶表现出优异的生物相容性，这使我们能够直接3D打印生物结构和组织。AP水凝胶出色的光学透明度为3D打印隐形眼镜提供了可能性。更重要的是，AP水凝胶能够与商用3D打印弹性体形成强界面结合，这使我们能够直接3D打印水凝胶-弹性体混合结构，如在弹性体基质上打印有导电水凝胶电路的柔性电子板。
