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采用结构方程模型探讨韩国女性骨密度的影响因素。

A Structural Equation Modelling Approach to Determine Factors of Bone Mineral Density in Korean Women.

机构信息

Department of Food and Nutrition, Gyeongsang National University, Jinju 52828, Korea.

Department of Food and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University, Jinju 52828, Korea.

出版信息

Int J Environ Res Public Health. 2021 Nov 6;18(21):11658. doi: 10.3390/ijerph182111658.

DOI:10.3390/ijerph182111658
PMID:34770170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8583138/
Abstract

BACKGROUND

no studies have assessed the associations of nutrient intake, physical activity, age, and body mass index (BMI) with bone mineral density (BMD) using structural equation modelling (SEM) in Korean women. The aim of this study was to examine the effects of nutrient intakes, physical activity, and body mass index (BMI) on BMD in Korean premenopausal and postmenopausal women, with the SEM approach, based on the fourth and fifth Korea National Health and Nutrition Examination Surveys (KNHANES) 2008-2011.

METHODS

SEM analysis was performed with 4160 women (2863 premenopausal women and 1297 postmenopausal women) aged 30-75 years in order to investigate total, direct, or mediating effects of nutrient intake, physical activity, age, and BMI on BMD. Model sensitivity to external misspecification and statistical significance of SEM was determined by phantom variables and bootstrapping. Reliability assessment of the SEM was done by Cronbach's alpha.

RESULTS

a direct effect of minerals (potassium, calcium, and phosphorus) on BMD (total femur, femoral neck, lumbar spine, and whole body) was observed in premenopausal and postmenopausal women ( = 0.045 and = 0.048, respectively). Age and BMI showed a total effect on BMD in premenopausal and postmenopausal women ( = 0.002, respectively).

CONCLUSIONS

our study suggests that mineral intake (potassium, calcium, and phosphorus), age, and BMI are major contributors to BMD in Korean premenopausal and postmenopausal women aged 30-75 years.

摘要

背景

此前尚无研究采用结构方程模型(SEM)评估营养摄入、身体活动、年龄和体重指数(BMI)与骨密度(BMD)之间的关系。本研究旨在使用韩国第四次和第五次全国健康和营养检查调查(KNHANES)2008-2011 年的数据,通过 SEM 方法,探讨营养摄入、身体活动和 BMI 对韩国绝经前和绝经后妇女 BMD 的影响。

方法

对 4160 名年龄在 30-75 岁的女性(2863 名绝经前女性和 1297 名绝经后女性)进行 SEM 分析,以调查营养素摄入、身体活动、年龄和 BMI 对 BMD 的总效应、直接效应或中介效应。通过虚拟变量和自举法确定 SEM 对外在误设定的敏感性和统计显著性。采用 Cronbach's alpha 对 SEM 的可靠性进行评估。

结果

在绝经前和绝经后妇女中,矿物质(钾、钙和磷)对 BMD(全股骨、股骨颈、腰椎和全身)有直接影响( = 0.045 和 = 0.048)。年龄和 BMI 对绝经前和绝经后妇女的 BMD 均有总效应( = 0.002)。

结论

本研究表明,矿物质(钾、钙和磷)摄入、年龄和 BMI 是 30-75 岁韩国绝经前和绝经后妇女 BMD 的主要影响因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/7832d15c8e4b/ijerph-18-11658-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/386c02daa714/ijerph-18-11658-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/436e6379d1e0/ijerph-18-11658-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/e39ea77b2498/ijerph-18-11658-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/fe92dc2a3ded/ijerph-18-11658-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/7832d15c8e4b/ijerph-18-11658-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/386c02daa714/ijerph-18-11658-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/436e6379d1e0/ijerph-18-11658-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/e39ea77b2498/ijerph-18-11658-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/fe92dc2a3ded/ijerph-18-11658-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d80/8583138/7832d15c8e4b/ijerph-18-11658-g005.jpg

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