Basirun Carin, Ferlazzo Melanie L, Howell Nicholas R, Liu Guo-Jun, Middleton Ryan J, Martinac Boris, Narayanan S Anand, Poole Kate, Gentile Carmine, Chou Joshua
School of Biomedical Engineering, Faculty of Engineering and Information Technology, University of Technology Sydney, Sydney, NSW, Australia.
Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia.
Front Cell Dev Biol. 2021 Oct 29;9:750775. doi: 10.3389/fcell.2021.750775. eCollection 2021.
In recent years, there has been an increasing interest in space exploration, supported by the accelerated technological advancements in the field. This has led to a new potential environment that humans could be exposed to in the very near future, and therefore an increasing request to evaluate the impact this may have on our body, including health risks associated with this endeavor. A critical component in regulating the human pathophysiology is represented by the cardiovascular system, which may be heavily affected in these extreme environments of microgravity and radiation. This mini review aims to identify the impact of microgravity and radiation on the cardiovascular system. Being able to understand the effect that comes with deep space explorations, including that of microgravity and space radiation, may also allow us to get a deeper understanding of the heart and ultimately our own basic physiological processes. This information may unlock new factors to consider with space exploration whilst simultaneously increasing our knowledge of the cardiovascular system and potentially associated diseases.
近年来，在该领域技术加速进步的支持下，太空探索越来越受关注。这带来了一种人类在不久的将来可能会接触到的新潜在环境，因此，对于评估这可能对我们身体产生的影响，包括与这项活动相关的健康风险的要求也日益增加。调节人体病理生理学的一个关键组成部分是心血管系统，在微重力和辐射这些极端环境中，心血管系统可能会受到严重影响。本综述旨在确定微重力和辐射对心血管系统的影响。能够了解深空探索带来的影响，包括微重力和太空辐射的影响，也可能使我们更深入地了解心脏，并最终了解我们自己的基本生理过程。这些信息可能会揭示太空探索中需要考虑的新因素，同时增加我们对心血管系统及潜在相关疾病的认识。
