与新型冠状病毒肺炎感染相关的急性黄斑神经视网膜病变
Acute macular neuroretinopathy associated with COVID-19 infection.
作者信息
David James A, Fivgas George D
机构信息
Louisiana State University Health Sciences Center, Department of Ophthalmology, 533 Bolivar St, Room 451B, New Orleans, LA, 70112, USA.
The Retina Center, 7777 Hennessy Blvd, Ste 3000, Baton Rouge, LA, 70808, USA.
出版信息
Am J Ophthalmol Case Rep. 2021 Dec;24:101232. doi: 10.1016/j.ajoc.2021.101232. Epub 2021 Nov 10.
PURPOSE
To report a case of bilateral acute macular neuroretinopathy (AMN) associated with a COVID-19 infection.
OBSERVATIONS
A 22-year-old female was referred for evaluation of bilateral scotomas concurrent with a mildly symptomatic COVID-19 infection. Exam showed normal visual acuity, bilateral reddish-brown petaloid retinal lesions which were hyporeflective on near infrared (NIR) optical coherence tomography (OCT), and had associated hypoperfusion of the deep vascular plexus on OCT-angiography (OCT-A) consistent with bilateral AMN. At follow-up, scotomas and retinal findings on near infrared imaging and spectral-domain optical coherence tomography had only slightly improved.
CONCLUSIONS
COVID-19 has been documented to be the etiology of a growing number of ocular manifestations including microvascular events. We report a case of bilateral acute macular neuroretinopathy in a patient with a recent diagnosis of COVID-19 infection that had persistent symptoms and findings at six month follow-up.
目的
报告一例与新型冠状病毒肺炎（COVID-19）感染相关的双侧急性黄斑神经视网膜病变（AMN）病例。
观察结果
一名22岁女性因双侧暗点同时伴有轻度症状性COVID-19感染而前来接受评估。检查显示视力正常，双侧可见红棕色花瓣状视网膜病变，在近红外（NIR）光学相干断层扫描（OCT）上呈低反射性，并且在OCT血管造影（OCT-A）上伴有深层血管丛灌注不足，符合双侧AMN表现。在随访中，近红外成像和光谱域光学相干断层扫描显示的暗点和视网膜表现仅略有改善。
结论
已有文献证明，COVID-19是包括微血管事件在内的越来越多眼部表现的病因。我们报告了一例近期诊断为COVID-19感染的患者发生双侧急性黄斑神经视网膜病变的病例，该患者在六个月随访时仍有持续症状和检查结果。
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