Diagnostic and Interventional Radiology Unit, ASST Settelaghi, Varese, Italy.
Insubria University, Varese, Italy.
Acta Diabetol. 2022 Feb;59(2):147-161. doi: 10.1007/s00592-021-01826-3. Epub 2021 Nov 15.
Translational medicine, experimental medicine and experimental animal models, in particular mice and rats, represent a multidisciplinary field that has made it possible to achieve, in the last decades, important scientific progress. In this review, we have summarized the most frequently used imaging animal models, such as ultrasound (US), micro-CT, MRI and the optical imaging methods, and their main implications in diagnostic and therapeutic fields, with a particular focus on diabetes mellitus, a multifactorial disease extremely widespread among the general population.
转化医学、实验医学和实验动物模型,尤其是小鼠和大鼠,代表了一个多学科领域,使得过去几十年取得了重要的科学进展。在这篇综述中,我们总结了最常用的成像动物模型,如超声(US)、微 CT、MRI 和光学成像方法,及其在诊断和治疗领域的主要应用,特别关注糖尿病,这是一种在普通人群中极为普遍的多因素疾病。