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海鲜源狄氏弧菌中基因的出现。

Emergence of the Gene in Vibrio diabolicus of Seafood Origin.

机构信息

Department of Marine Biology, College of Oceanography, Hohai Universitygrid.257065.3, Nanjing, P. R. China.

Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, P. R. China.

出版信息

Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0181921. doi: 10.1128/AAC.01819-21. Epub 2021 Nov 15.

DOI:10.1128/AAC.01819-21
PMID:34780265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8765225/
Abstract

The emergence and transmission of multidrug resistance (MDR) gene have incurred great public health concerns worldwide. Recently, Gram-negative pathogens were found to carry by various mobile elements. Here, we investigated a -positive Vibrio diabolicus isolate by phenotyping and genomic analysis and found in a translocatable structure (IS---IS) among the MDR region in pNV27-cfr-208K, an emerging MDR plasmid in species. This study highlights the necessity of surveillance of in bacteria of diverse origins.

摘要

多药耐药(MDR)基因的出现和传播引起了全球公共卫生的极大关注。最近,革兰氏阴性病原体被发现通过各种移动元件携带 。在这里,我们通过表型和基因组分析研究了一株携带 的 阳性 恶魔弧菌分离株,并在 pNV27-cfr-208K 中的 MDR 区域中发现了一个可移动结构(IS---IS),该质粒是 种属中的一种新兴 MDR 质粒。本研究强调了对不同来源细菌中 的监测的必要性。

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本文引用的文献

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Identification of a Novel Plasmid-Mediated Carbapenemase-Encoding Gene, , in Vibrio diabolicus.在恶魔弧菌中发现一种新型质粒介导碳青霉烯酶编码基因 。
Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0020621. doi: 10.1128/AAC.00206-21.
2
Mobile Oxazolidinone Resistance Genes in Gram-Positive and Gram-Negative Bacteria.革兰阳性菌和革兰阴性菌中的移动恶唑烷酮类耐药基因。
Clin Microbiol Rev. 2021 Jun 16;34(3):e0018820. doi: 10.1128/CMR.00188-20. Epub 2021 Jun 2.
3
First detection of the multiresistance gene cfr in Escherichia coli from retail vegetables, China.在中国零售蔬菜的大肠杆菌中首次检测到多重耐药基因cfr 。
Int J Antimicrob Agents. 2021 May;57(5):106348. doi: 10.1016/j.ijantimicag.2021.106348. Epub 2021 Apr 20.
4
Rapid Increase in the IS-Mediated Gene in Isolates with IncP and IncX4 Plasmids and Co-Existing and Genes in a Swine Farm.具有IncP和IncX4质粒的分离株中IS介导基因的快速增加以及猪场中基因的共存
Pathogens. 2021 Jan 3;10(1):33. doi: 10.3390/pathogens10010033.
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ResFinder 4.0 for predictions of phenotypes from genotypes.ResFinder 4.0 用于基因型到表型的预测。
J Antimicrob Chemother. 2020 Dec 1;75(12):3491-3500. doi: 10.1093/jac/dkaa345.
6
Characterization of a porcine Proteus cibarius strain co-harbouring tet(X6) and cfr.一株同时携带tet(X6)和cfr的食蟹变形杆菌猪源菌株的特性分析
J Antimicrob Chemother. 2020 Jun 1;75(6):1652-1654. doi: 10.1093/jac/dkaa047.
7
Pushing the limits of de novo genome assembly for complex prokaryotic genomes harboring very long, near identical repeats.为含有超长、近乎完全相同重复序列的复杂原核基因组的从头基因组组装推陈出新。
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oriTfinder: a web-based tool for the identification of origin of transfers in DNA sequences of bacterial mobile genetic elements.oriTfinder:一种基于网络的工具,用于鉴定细菌移动遗传元件 DNA 序列中转座子的起源。
Nucleic Acids Res. 2018 Jul 2;46(W1):W229-W234. doi: 10.1093/nar/gky352.
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Efficient generation of complete sequences of MDR-encoding plasmids by rapid assembly of MinION barcoding sequencing data.通过快速组装 MinION 条形码测序数据,高效生成完整的 MDR 编码质粒序列。
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