Department of Medicine, Sumeru City Hospital, Lalitpur, Nepal.
Department of Intensive Care, Sumeru City Hospital, Lalitpur, Nepal.
JNMA J Nepal Med Assoc. 2021 Aug 12;59(240):808-811. doi: 10.31729/jnma.6710.
Coronavirus Disease has become a global pandemic after its emergence at the end of 2019 as a cluster of pneumonia. Apart from respiratory symptoms, neurologic complications are also common, mostly in hospitalized patients. More than 80 percent of patients have neurological symptoms during their disease course of which most common is encephalopathy. However, data on neurological complications like Guillain-Barré syndrome associated with coronavirus-2019 are scarce. Here, we report a case of a 64-years-old female patient with typical clinical and electrophysiological manifestations of Acute motor axonal neuropathy variant, who was reported positive with polymerase chain reaction for severe acute respiratory syndrome coronavirus-2, 13 days before the onset of acute bilateral weakness of extremities, areflexia, and normal sensory examination. Cerebrospinal fluid and electrophysiological examination were also suggestive. The neurological symptoms improved during treatment with immunoglobulins. Quick recognition of symptoms and diagnosis is important in the management of Guillain-Barré syndrome associated with coronavirus-2019.
2019 年末,一种肺炎聚集性疾病出现后,冠状病毒疾病已成为全球大流行。除了呼吸道症状外,神经并发症也很常见,主要发生在住院患者中。超过 80%的患者在疾病过程中有神经系统症状,其中最常见的是脑病。然而,与 2019 年冠状病毒相关的吉兰-巴雷综合征等神经系统并发症的数据很少。在这里,我们报告了一例 64 岁女性患者,其具有急性运动轴索性神经病变异的典型临床和电生理表现,在急性双侧肢体无力、反射消失和正常感觉检查出现 13 天前,聚合酶链反应检测到严重急性呼吸综合征冠状病毒-2 呈阳性。脑脊液和电生理检查也提示阳性。免疫球蛋白治疗期间神经系统症状改善。快速识别症状和诊断对于管理与 2019 年冠状病毒相关的吉兰-巴雷综合征很重要。