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从筛查到抗丙型肝炎病毒治疗以及肝癌/失代偿期肝硬化的无缝支持:丙型肝炎病毒消除补贴计划。

Seamless support from screening to anti-HCV treatment and HCC/ decompensated cirrhosis: Subsidy programs for HCV elimination.

作者信息

Setoyama Hiroko, Tanaka Yasuhito, Kanto Tatsuya

机构信息

Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

Hepatitis Information Center, The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan.

出版信息

Glob Health Med. 2021 Oct 31;3(5):335-342. doi: 10.35772/ghm.2021.01079.

Abstract

Viral hepatitis poses a major public health problem in Japan. Chronic viral hepatitis is a progressive liver disease that eventually develops into liver cirrhosis and liver cancer. Since nucleic acid analog therapy for hepatitis B and interferon-free therapy for hepatitis C have made it possible to control the disease status or eliminate the viruses, it is very important that more people receive hepatitis virus tests to confirm the presence of infection at an early stage, and that patients with hepatitis detected by the tests receive appropriate medical care. Currently, the government of Japan is implementing comprehensive measures for hepatitis control based on five key strategies. Moreover, the goal listed in the Basic Guidelines on Hepatitis Measures is to reduce the frequency of progression of hepatitis to cirrhosis or liver cancer through a scheme consisting of testing people for hepatitis, getting those who test positive to visit a medical institution and receive treatment, and providing appropriate and high-quality hepatitis care through specialized medical institutions and regional core centers for the management of liver disease. To achieve the goal, various subsidy programs including an expense subsidy system for hepatitis treatment have been implemented in Japan. It is important for healthcare professionals to have sufficient knowledge of public support for efficient hepatitis C virus (HCV)-related liver disease detection and care.

摘要

病毒性肝炎在日本构成了一个重大的公共卫生问题。慢性病毒性肝炎是一种渐进性肝病,最终会发展为肝硬化和肝癌。由于针对乙型肝炎的核酸类似物疗法和针对丙型肝炎的无干扰素疗法已使控制疾病状态或清除病毒成为可能,因此让更多人接受肝炎病毒检测以在早期确认感染情况,以及让检测出肝炎的患者接受适当医疗护理非常重要。目前,日本政府正在基于五项关键策略实施全面的肝炎控制措施。此外,《肝炎对策基本方针》中列出的目标是通过一个包括对人们进行肝炎检测、让检测呈阳性者前往医疗机构接受治疗,以及通过专门医疗机构和区域肝病管理核心中心提供适当和高质量的肝炎护理的方案,来降低肝炎发展为肝硬化或肝癌的频率。为实现这一目标,日本实施了包括肝炎治疗费用补贴制度在内的各种补贴计划。医疗保健专业人员充分了解公众对高效检测和护理丙型肝炎病毒(HCV)相关肝病的支持非常重要。

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