Alyafi Tawfeik, Al-Marzouki Al-Hasan H, Al Hassani Abdulaziz N
Plastic and Reconstructive Surgery, National Guard Health Affairs, Jeddah, SAU.
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Cureus. 2021 Oct 11;13(10):e18671. doi: 10.7759/cureus.18671. eCollection 2021 Oct.
Amongst various interventions for burns and inhalation injuries, hyperbaric oxygen therapy (HBOT) has recently been widely integrated as an adjunctive management of care due to its therapeutic properties in reducing tissue hypoxia, pathological inflammation, and augmenting neovascularization. However, the limitation of human clinical trials and data undermines its efficacy to be implemented as an adjunctive therapeutic modality in burns. The purpose of the literature review is to determine the efficacy of HBOT as an adjunct to standard management in burns. A review of the literature was done by searching PubMed, Cochrane, Medline, EMBASE, and Google Scholar for papers addressing the comparison of therapeutic outcomes between HBOT and non-HBOT in burns. Current research findings are conflicting, and the use of HBOT as an adjunct in burns management is still controversial. Therefore there is still a need for more data and research on the therapeutic benefits of HBOT in burn management.
在针对烧伤和吸入性损伤的各种干预措施中，高压氧疗法（HBOT）近来已被广泛纳入辅助治疗方案，因为它在减轻组织缺氧、病理性炎症以及促进新血管形成方面具有治疗特性。然而，人体临床试验和数据的局限性削弱了其作为烧伤辅助治疗手段的有效性。本综述的目的是确定高压氧疗法作为烧伤标准治疗辅助手段的疗效。通过检索PubMed、Cochrane、Medline、EMBASE和谷歌学术，对相关文献进行了综述，以查找涉及高压氧疗法与非高压氧疗法在烧伤治疗效果比较方面的论文。当前的研究结果相互矛盾，在烧伤治疗中使用高压氧疗法作为辅助手段仍存在争议。因此，仍需要更多关于高压氧疗法在烧伤治疗中益处的数据和研究。
